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Vol. 72, No. 4, 2005
Issue release date: 2005
Section title: Original Paper
Digestion 2005;72:212–218
(DOI:10.1159/000089727)

Use of Proton Pump Inhibitors: An Exploration of the Attitudes, Knowledge and Perceptions of General Practitioners

Raghunath A.S. · Hungin A.P.S. · Cornford C.S. · Featherstone V.
aSchool for Health, University of Durham, Queen’s Campus, Wolfson Research Institute, Stockton-on-Tees, and b Wold Research Network, Hull and East Yorkshire, Hull, UK

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 8/4/2005
Accepted: 9/20/2005
Published online: 12/16/2005

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 3

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG

Abstract

Background/Aim: Proton pump inhibitor (PPI) prescribing is costly. The volume of PPI prescription is also increasing, despite little evidence that would justify the increase. General practitioners (GPs) are largely responsible for PPI prescribing, yet knowledge of their views concerning PPIs which might explain the apparent anomaly of prescribing costly drugs without justification is lacking. The aim of this study is therefore to investigate how GPs make decisions about PPI prescribing. Method: Qualitative study design using focus groups of 34 GPs and 15 training GPs analysed according to grounded theory principles and use of constant comparative analysis. Results:The participants showed agreement about the clinical factors potentially relevant to PPI prescribing such as age of presentation and endoscopy, issues of Helicobacter pylori eradication and issues around malignancy. There was considerable controversy, however, as to how to apply those factors in real clinical consultations. GPs in training and academic GPs tended to be more conservative; service-based GPs more pragmatic. There was agreement about the need to review long-term PPI medication, but controversy about whether the conventional ‘step-up step-down’ approach was realistic in practice. Good agreement was apparent about the effectiveness, the cost implications, and some of the ethical issues surrounding PPIs, but considerable controversy as to how far such factors should influence prescribing of PPIs. Conclusion:The GPs showed good understanding and knowledge of the issues surrounding PPI prescribing. There was considerable controversy as to how such knowledge should be translated into practice.


  

Author Contacts

Dr. A.S. Raghunath
School for Health, University of Durham
Queen’s Campus, Wolfson Research Institute, University Boulevard
Stockton-on-Tees TS17 6BH (UK)
Tel. +44 1482 336810, Fax +44 1482 336824, E-Mail Raghu@nath.freeserve.co.uk

  

Article Information

Received: August 4, 2005
Accepted: September 20, 2005
Published online: November 11, 2005
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 3, Number of References : 35

  

Publication Details

Digestion (International Journal of Gastroenterology)

Vol. 72, No. 4, Year 2005 (Cover Date: 2005)

Journal Editor: Beglinger, C. (Basel)
ISSN: 0012–2823 (print), 1421–9867 (Online)

For additional information: http://www.karger.com/DIG


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 8/4/2005
Accepted: 9/20/2005
Published online: 12/16/2005

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 3

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: http://www.karger.com/DIG


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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