Extensive gross genomic rearrangements between chicken and Old World vultures (Falconiformes: Accipitridae)Nanda I. · Karl E. · Volobouev V. · Griffin D.K. · Schartl M. · Schmid M.
aDepartment of Human Genetics, University of Würzburg, Würzburg (Germany); bDépartement de Systématique et Evolution, Muséum National d’Histoire Naturelle, Paris (France); cDepartment of Biosciences, University of Kent, Kent (UK); dPhysiologische Chemie I, Biozentrum, University of Würzburg, Würzburg (Germany)
The karyotypes of most birds consist of a small number of macrochromosomes and numerous microchromosomes. Intriguingly, most accipitrids which include hawks, eagles, kites, and Old World vultures (Falconiformes) show a sharp contrast to this basic avian karyotype. They exhibit strikingly few microchromosomes and appear to have been drastically restructured during evolution. Chromosome paints specific to the chicken (GGA) macrochromosomes 1–10 were hybridized to metaphase spreads of three species of Old World vultures (Gyps rueppelli, Gyps fulvus, Gypaetus barbatus). Paints of GGA chromosomes 6–10 hybridize only to single chromosomes or large chromosome segments, illustrating the existence of high chromosome homology. In contrast, paints of the large macrochromosomes 1–5 show split hybridization signals on the chromosomes of the accipitrids, disclosing excessive chromosome rearrangements which is in clear contrast to the high degree of chromosome conservation substantiated from comparative chromosome painting in other birds. Furthermore, the GGA chromosome paint hybridization patterns reveal remarkable interchromosomal conservation among the two species of the genus Gyps.
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Department of Human Genetics, University of Würzburg, Biocenter
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Supported by grants from the Deutsche Forschungsgemeinschaft (Schm 484/ 21-1 and 21-2).
Manuscript received: 21 July 2005
Accepted in revised form for publication by T. Haaf,: 10 August 2005.
Number of Print Pages : 10
Number of Figures : 5, Number of Tables : 1, Number of References : 33
Cytogenetic and Genome Research
Vol. 112, No. 3-4, Year 2006 (Cover Date: February 2006)
Journal Editor: Schmid, M. (Würzburg)
ISSN: 1424–8581 (print), 1424–859X (Online)
For additional information: http://www.karger.com/CGR