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Vol. 65, Suppl. 3, 2006
Issue release date: April 2006
Section title: Early Postnatal Growth
Horm Res 2006;65:70–74
(DOI:10.1159/000091509)

Hormonal Regulation of Postnatal Growth in Children Born Small for Gestational Age

Cianfarani S. · Ladaki C. · Geremia C.
‘Rina Balducci’ Centre of Paediatric Endocrinology, Department of Public Health and Cell Biology, Tor Vergata University, Rome, Italy

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Article / Publication Details

First-Page Preview
Abstract of Early Postnatal Growth

Published online: 4/10/2006

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0

ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)

For additional information: http://www.karger.com/HRP

Abstract

Children born small for gestational age (SGA) are at high risk of permanent short stature, with approximately 10% continuing to have stature below the third centile throughout childhood and adolescence and into adulthood. The mechanisms involved in catch-up growth, and those that prevent catch-up growth, are still unknown. To date, no reliable anthropometric or endocrine parameter predictive of postnatal catch-up growth has been identified. However, subtle abnormalities in the growth hormone-insulin-like growth factor axis, the hypothalamic-pituitary-adrenal axis and thyroid function have been described, and a mechanism involving intrauterine programming of hypothalamic-pituitary function has been proposed.


  

Author Contacts

S. Cianfarani
‘Rina Balducci’ Centre of Paediatric Endocrinology
Department of Public Health and Cell Biology, Room E-178
Tor Vergata University, Via Montpellier 1, IT–00133 Rome (Italy)
Tel. +39 06 5100 2314, Fax +39 06 5917 415, E-Mail stefano.cianfarani@uniroma2.it

  

Article Information

Published online: April 10, 2006
Number of Print Pages : 5
Number of Figures : 3, Number of Tables : 0, Number of References : 30

  

Publication Details

Hormone Research (From Developmental Endocrinology to Clinical Research)

Vol. 65, No. Suppl. 3, Year 2006 (Cover Date: April 2006)

Journal Editor: Czernichow, P. (Paris)
ISSN: 0301–0163 (print), 1423–0046 (Online)

For additional information: http://www.karger.com/HRE


Article / Publication Details

First-Page Preview
Abstract of Early Postnatal Growth

Published online: 4/10/2006

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0

ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)

For additional information: http://www.karger.com/HRP


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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