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Table of Contents
Vol. 22, No. 1, 2006
Issue release date: June 2006
Section title: Original Research Article
Dement Geriatr Cogn Disord 2006;22:1–7
(DOI:10.1159/000092845)

Differences in Risk Factors for Dementia with Neurodegenerative Traits and for Vascular Dementia

Wehr H.a · Bednarska-Makaruk M.a · Łojkowska W.b · Graban A.b · Hoffman-Zacharska D.c · Kuczyńska-Zardzewiały A.d · Mrugała J.d · Rodo M.a · Bochyńska A.b · Sułek A.a · Ryglewicz D.b
aDepartment of Genetics and bFirst Department of Neurology, Institute of Psychiatry and Neurology, cDepartment of Neurogenetics, Clinic of Neurology, Epileptology and Sleep Disorders, Institute of Mother and Child, and dDepartment of Neurology, Wolski Hospital, Warsaw, Poland

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Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Received: June 07, 2005
Published online: June 19, 2006
Issue release date: June 2006

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 5

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

Abstract

In 229 patients with dementia and in 144 control subjects, polymorphisms of apolipoprotein E (ApoE), low-density-lipoprotein (LDL)-receptor-related protein, α2-macroglobulin, interleukin (IL) 1β, angiotensin-converting enzyme and of methylene tetrahydrofolate reductase genes were investigated. In plasma, antibodies against Chlamydia pneumoniae and lipids were determined. Dementia was classified as probable Alzheimer’s disease (AD), probable dementia of vascular origin (VaD) and mixed dementia (MD). An association of the disease with ApoE and IL-1β polymorphism and increased levels of LDL cholesterol were observed in AD and in MD but not in VaD.

© 2006 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Received: June 07, 2005
Published online: June 19, 2006
Issue release date: June 2006

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 5

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.