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Vol. 75, No. 4, 2006
Issue release date: June 2006
Section title: Regular Article
Psychother Psychosom 2006;75:220–228
(DOI:10.1159/000092892)

Comparison of Sleep Condition and Sleep-Related Psychological Activity after Cognitive-Behavior and Pharmacological Therapy for Chronic Insomnia

Wu R. · Bao J. · Zhang C. · Deng J. · Long C.
aDepartment of Medical Psychology, Peking University Health Science Center, bBeijing Institute for Neurosis, Capital University of Medication Science, and cSleep Disorders Center of Beijing Second Hospital, Beijing, P.R. China

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Article / Publication Details

First-Page Preview
Abstract of Regular Article

Published online: 6/19/2006

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 2

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS

Abstract

Background: Previous studies of insomnia focused mainly on the improvement of sleep condition and ignored the effects of sleep-related psychological activity and daytime function after pharmacological and behavioral treatments. We compared the clinical effects of both therapies on sleep condition, sleep-related psychological activity and daytime function in chronic insomnia. Methods: Seventy-one patients with chronic insomnia were randomly divided into 4 groups and either received cognitive-behavior therapy (CBT, n = 19), pharmacological therapy (PCT, n = 17), CBT plus medication (Combined, n = 18) or placebo (n = 17). The treatments lasted for 8 weeks with follow-ups conducted at 3 and 8 months. On the day after treatment ended, all patients were assessed using a polysomnogram (PSG), a sleep diary and a psychological assessment. Results: The three active treatments were more effective than placebo at the time the treatments were completed. Subjective sleep-onset latency, sleep efficacy and total sleep time were better in the PCT group than in the CBT group. At the 3-month follow-up, subjective and objective sleep-onset latency, sleep efficacy and total sleep time were better in the CBT group than in both the PCT and the Combined group. At the 8-month follow-up, the CBT group showed a steady comfortable sleep state, while the PCT and Combined groups were gradually returning to the pre-treatment condition. The Combined group showed a variable long-term effect. On the other hand, pre-sleep arousal at nighttime, dysfunctional beliefs about sleep as well as daytime functioning in the CBT group not only improved, but was better than in the other active treatment groups. Conclusion: Medication and Combined therapy produced a short-term effect on chronic insomnia while CBT had a long-term effect of improved sleep-related psychological activity and daytime functioning.


  

Author Contacts

Rengang Wu, MD
Department of Medical Psychology
Peking University Health Science Center
Beijing, 100083 (P.R. China)
Tel. +86 10 6294 2726, Fax +86 10 8280 2494, E-Mail rengangwu66@hotmail.com

  

Article Information

Number of Print Pages : 9
Number of Figures : 2, Number of Tables : 2, Number of References : 35

  

Publication Details

Psychotherapy and Psychosomatics

Vol. 75, No. 4, Year 2006 (Cover Date: June 2006)

Journal Editor: Fava, G.A. (Bologna)
ISSN: 0033–3190 (print), 1423–0348 (Online)

For additional information: http://www.karger.com/PPS


Article / Publication Details

First-Page Preview
Abstract of Regular Article

Published online: 6/19/2006

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 2

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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