Journal Mobile Options
Table of Contents
Vol. 19, No. 4, 2006
Issue release date: July 2006
Section title: Original Paper
Skin Pharmacol Appl Skin Physiol 2006;19:224–231
(DOI:10.1159/000093118)

Antioxidant Supplements Improve Parameters Related to Skin Structure in Humans

Heinrich U. · Tronnier H. · Stahl W. · Béjot M. · Maurette J.-M.
aInstitute of Experimental Dermatology, University of Witten/Herdecke, Witten, bInstitute of Biochemistry and Molecular Biology I, University of Düsseldorf, Düsseldorf, Germany, and cLaboratoire Oenobiol, Paris, France

Do you have an account?

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger (new!)
  • Unrestricted printing, no saving restrictions for personal use
  • Reduced rates with a PPV account
read more

Direct: USD 38.00
Account: USD 26.50

Select

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe

  • Automatic perpetual access to all articles of the subscribed year(s)
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 7/12/2005
Accepted: 10/14/2005
Published online: 7/14/2006

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 4

ISSN: 1660-5527 (Print)
eISSN: 1660-5535 (Online)

For additional information: http://www.karger.com/SPP

Abstract

In the present study we investigated the influence of two different antioxidant supplements composed of carotenoids, vitamin E and selenium on parameters related to skin health and skin aging. Thirty-nine volunteers with healthy, normal skin of skin type 2 were divided into 3 groups (n = 13) and supplemented for a period of 12 weeks. Group 1 received a mixture of lycopene (3 mg/day), lutein (3 mg/day), β-carotene (4.8 mg/day), α-tocopherol (10 mg/day) and selenium (75 µg/day). Group 2 was supplemented with a mixture of lycopene (6 mg/day), β-carotene (4.8 mg/day), α-tocopherol (10 mg/day) and selenium (75 µg/day). Group 3 was the placebo control. Upon supplementation serum levels of selected carotenoids increased in both verum groups. Skin density and thickness were determined by ultrasound measurements. A significant increase for both parameters was determined in the verum groups. Roughness, scaling, smoothness and wrinkling of the skin were determined by Surface Evaluation of Living Skin (Visioscan). Roughness and scaling were improved by the supplementation with antioxidant micronutrients. In the placebo group no changes were found for any of the parameters.


  

Author Contacts

Prof. Dr. Ulrike Heinrich
Institut für Experimentelle Dermatologie, Universität Witten/Herdecke
Alfred-Herrhausen-Strasse 44 (FEZ)
DE–58455 Witten (Germany)
Tel. +49 2302 2826 300, Fax +49 2302 2826 326, E-Mail ulrike.heinrich@uni-wh.de

  

Article Information

Received: July 12, 2005
Accepted after revision: October 14, 2005
Published online: May 4, 2006
Number of Print Pages : 8
Number of Figures : 4, Number of Tables : 4, Number of References : 24

  

Publication Details

Skin Pharmacology and Physiology (Journal of Pharmacological and Biophysical Research)

Vol. 19, No. 4, Year 2006 (Cover Date: July 2006)

Journal Editor: Lademann, J. (Berlin)
ISSN: 1660–5527 (print), 1660–5535 (Online)

For additional information: http://www.karger.com/SPP


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 7/12/2005
Accepted: 10/14/2005
Published online: 7/14/2006

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 4

ISSN: 1660-5527 (Print)
eISSN: 1660-5535 (Online)

For additional information: http://www.karger.com/SPP


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.