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Original Paper

Periodontitis Is an Important and Occult Source of Inflammation in Hemodialysis Patients

Kadiroglu A.K.a · Kadiroglu E.T.b · Sit D.a · Dag A.b · Yilmaz M.E.a

Author affiliations

aDepartment of Nephrology, Medical Faculty, and bDepartment of Periodontology, Dental Faculty, University of Dicle, Diyarbakir, Turkey

Related Articles for ""

Blood Purif 2006;24:400–404

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: February 15, 2006
Accepted: April 12, 2006
Published online: August 14, 2006
Issue release date: August 2006

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 5

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: http://www.karger.com/BPU

Abstract

Aim: To evaluate the association between C-reactive protein (CRP) levels and the periodontal status of hemodialysis (HD) patients. Methods: 41 HD patients on rHuEPO therapy were enrolled in the study. Hematologic and biochemical parameters and CRP levels were recorded. The plaque index, gingival index, probing pocket depth and periodontal disease index were used to identify periodontal disease. The patients were divided into 2 groups: group 1 (n = 21), high CRP, and group 2 (n = 20), normal CRP. Results: After periodontal therapy, while the mean CRP level and erythrocyte sedimentation rate declined from 30.46 to 10.36 (p = 0.001) and from 93.4 to 35.8 mg/l (p = 0.001), respectively, the hemoglobin level increased from 9.4 to 10.6 g/dl (p = 0.009) and hematocrit level from 28.2 to 32.0% (p = 0.008) in group 1. Conclusion: Periodontitis is an important and occult source of chronic inflammation and increases the CRP levels in HD patients. Periodontitis can cause hyporesponsiveness to rHuEPO treatment and decrease the hemoglobin levels.

© 2006 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: February 15, 2006
Accepted: April 12, 2006
Published online: August 14, 2006
Issue release date: August 2006

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 5

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: http://www.karger.com/BPU


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