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Table of Contents
Vol. 213, No. 2, 2006
Issue release date: August 2006
Section title: Clinical and Laboratory Investigations
Dermatology 2006;213:102–110
(DOI:10.1159/000093848)

Work Limitations and Productivity Loss Are Associated with Health-Related Quality of Life but Not with Clinical Severity in Patients with Psoriasis

Schmitt J.M.a, d · Ford D.E.a, b, c
aDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, and Departments of bMedicine and cPsychiatry, Johns Hopkins University, Baltimore, Md., USA; dDepartment of Dermatology, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany

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Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigations

Received: January 06, 2006
Accepted: March 10, 2006
Published online: August 28, 2006
Issue release date: August 2006

Number of Print Pages: 9
Number of Figures: 1
Number of Tables: 3

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Background: According to current guidelines the cost of productivity loss should be considered in pharmacoeconomic analyses. The cost of health-related productivity loss in psoriasis patients is unknown. Objective: To estimate the cost of productivity loss in psoriasis and its association with health-related quality of life and clinical disease severity. Methods: Cross-sectional study, recruitment of adult participants through Internet advertisements. 201 (72.3%) out of 278 eligible participants completed the study. Health-related work productivity loss, quality of life and clinical severity of psoriasis were assessed by standardized instruments. Results: Indirect costs of productivity loss clearly exceed the total direct cost. In contrast to objective clinical disease severity, health-related quality of life (measured by the Dermatology Life Quality Index) is an independent predictor of work productivity. Conclusions: There is good reason to believe that intervention can reduce health-related productivity loss by improving patients’ quality of life. Savings from increased work productivity might offset comparatively high acquisition costs of biological agents.

© 2006 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigations

Received: January 06, 2006
Accepted: March 10, 2006
Published online: August 28, 2006
Issue release date: August 2006

Number of Print Pages: 9
Number of Figures: 1
Number of Tables: 3

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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