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Table of Contents
Vol. 68, No. 5, 2006
Issue release date: August 2006
Section title: Original Paper
ORL 2006;68:302–310
(DOI:10.1159/000094378)

An Approach for Precise Three-Dimensional Modeling of the Human Inner Ear

Li S.-F. · Zhang T.-Y. · Wang Z.-M.
Department of Otorhinolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, China

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/16/2005
Accepted: 2/9/2006
Published online: 9/6/2006

Number of Print Pages: 9
Number of Figures: 7
Number of Tables: 0

ISSN: 0301-1569 (Print)
eISSN: 1423-0275 (Online)

For additional information: http://www.karger.com/ORL

Abstract

For further morphological and physiological research, it is vital to establish precise three-dimensional models of the whole inner ear including the details of the membranous components. With the system of a projector and a high-resolution digital camera, 2 complete serial unstained celloidin sections of fresh human temporal bones were digitized as high-resolution images which were then sorted, calibrated, aligned and segmented using the 3D-Doctor software. Finally, 2 precise three-dimensional models of the inner ear were generated by simple surface rendering. The contours of tiny structures such as the crista ampullaris, the macula utriculi and the macula sacculi could be observed clearly. Our study suggests that it is technically feasible to employ complete serial unstained celloidin sections for precise three-dimensional reconstruction and that this helps reduce errors and laboratory workload. Moreover, the use of a high-resolution digital camera and the autoalignment function of 3D-Doctor further increase the accuracy of the models.


  

Author Contacts

Tian-Yu Zhang
Department of Otorhinolaryngology
Eye and ENT Hospital, Fudan University, 83 Fenyang Road
Shanghai, 200031 (China)
Tel. +86 21 6437 7134, Fax +86 21 6437 7151, E-Mail otozty@126.com

  

Article Information

Received: December 16, 2005
Accepted after revision: February 9, 2006
Published online: July 4, 2006
Number of Print Pages : 9
Number of Figures : 7, Number of Tables : 0, Number of References : 22

  

Publication Details

ORL (Journal for Oto-Rhino-Laryngology and Ist Related Specialties)

Vol. 68, No. 5, Year 2006 (Cover Date: August 2006)

Journal Editor: O'Malley, B.W., Jr. (Philadelphia, Pa.)
ISSN: 0301–1569 (print), 1423–0275 (Online)

For additional information: http://www.karger.com/ORL


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/16/2005
Accepted: 2/9/2006
Published online: 9/6/2006

Number of Print Pages: 9
Number of Figures: 7
Number of Tables: 0

ISSN: 0301-1569 (Print)
eISSN: 1423-0275 (Online)

For additional information: http://www.karger.com/ORL


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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