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Vol. 84, No. 4, 2006
Issue release date: September 2006
Section title: ASSFCN Proceedings
Stereotact Funct Neurosurg 2006;84:184–189
(DOI:10.1159/000095031)

Bilateral Anterior Cingulotomy for Refractory Obsessive-Compulsive Disorder: Long-Term Follow-Up Results

Jung H.H. · Kim C.-H. · Chang J.H. · Park Y.G. · Chung S.S. · Chang J.W.
Departments of aNeurosurgery and bPsychiatry, Brain Korea 21 Project for Medical Science, Brain Research Institute, Yonsei University College of Medicine, Seoul, South Korea

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Article / Publication Details

First-Page Preview
Abstract of ASSFCN Proceedings

Published online: 9/8/2006

Number of Print Pages: 6
Number of Figures: 5
Number of Tables: 1

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: http://www.karger.com/SFN

Abstract

Objective: To investigate the long-term efficacy and adverse cognitive effects of stereotactic bilateral anterior cingulotomy as a treatment for refractory obsessive-compulsive disorder (OCD) patients. Materials and Methods: Seventeen patients suffering from refractory OCD underwent stereotactic bilateral anterior cingulotomies and were followed for 24 months. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), the Clinical Global Impression and other neuropsychological tests were used to assess the efficacy and cognitive changes of cingulotomy. The tests were taken before and 12 and 24 months after surgery. Results: The mean improvement rate of the Y-BOCS score achieved from the baseline was 48%. Eight patients out of 17 met the responder criteria. During the 24-month follow-up, there were no significant adverse effects observed after surgery. Conclusions: Bilateral anterior cingulotomy was effective for the treatment of refractory OCD, and no other significant adverse cognitive effects on long-term follow-up were found.


  

Author Contacts

Jin Woo Chang, MD
Department of Neurosurgery
Yonsei University College of Medicine
Seoul 120-752 (South Korea)
Tel. +82 2 2228 2159, Fax +82 2 393 9979, E-Mail jchang@yumc.yonsei.ac.kr

  

Article Information

Published online: August 14, 2006
Number of Print Pages : 6
Number of Figures : 5, Number of Tables : 1, Number of References : 36

  

Publication Details

Stereotactic and Functional Neurosurgery

Vol. 84, No. 4, Year 2006 (Cover Date: September 2006)

Journal Editor: Roberts, D.W. (Lebanon, N.H.)
ISSN: 1011–6125 (print), 1423–0372 (Online)

For additional information: http://www.karger.com/SFN


Article / Publication Details

First-Page Preview
Abstract of ASSFCN Proceedings

Published online: 9/8/2006

Number of Print Pages: 6
Number of Figures: 5
Number of Tables: 1

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: http://www.karger.com/SFN


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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