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Original Research

The Implementation of Guidelines and Prognosis among Patients with Acute Coronary Syndromes Is Influenced by Physicians’ Perception of Antecedent Physical and Cognitive Status

Porter A.a · Iakobishvili Z.a · Dictiar R.b · Behar S.c · Hod H.c · Gottlieb S.c · Hammerman H.d · Zahger D.e · Hasdai D.a

Author affiliations

aDepartment of Cardiology, Rabin Medical Center, Petah Tikva, and Tel Aviv University, Tel Aviv, bIsraeli Center for Disease Control and cNeufeld Cardiac Research Center, Tel Hashomer, dRambam Medical Center, Haifa, and eSoroka Medical Center, Beer Sheva, Israel

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Cardiology 2007;107:422–428

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Article / Publication Details

First-Page Preview
Abstract of Original Research

Received: August 18, 2006
Accepted: October 02, 2006
Published online: February 19, 2007
Issue release date: May 2007

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: http://www.karger.com/CRD

Abstract

Background/Aims: Physicians’ perception of antecedent physical/cognitive status may account for the suboptimal implementation of acute coronary syndrome (ACS) guidelines. Methods: In an ACS survey of all cardiac wards, physicians’ perception of antecedent physical/cognitive status was prospectively recorded and categorized as either normal, mildly impaired or significantly impaired. We examined the impact of antecedent status on the use of evidence-based medications and procedures and on mortality. Results: Of the 2,021 patients, 1,025 (51%) had ST elevation. Impaired antecedent physical/cognitive status was diagnosed in 417 patients (20.6%), more commonly among non-ST-elevation patients (26.2 vs. 15.2%). Patients with impaired physical/cognitive status, with or without ST elevation, had significantly worse baseline demographic and clinical characteristics. They less often received aspirin, clopidogrel, platelet glycoprotein IIb/IIIa receptor antagonists, statins and β-adrenergic blockers, and significantly less often underwent in-hospital catheterization and revascularization. Reperfusion treatment was given significantly less frequently to ST elevation patients with impaired status (63.0% for normal vs. 50.8% and 33.3% for mildly and significantly impaired status, respectively; p = 0.001). After adjustment for differences in baseline characteristics, impaired antecedent status remained independently associated with lower use of these therapies and higher mortality rates. Conclusions: ACS guideline implementation is significantly influenced by physicians’ perception of antecedent physical/cognitive status, and thus is a crucial parameter for understanding ACS management and outcomes.

© 2007 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Research

Received: August 18, 2006
Accepted: October 02, 2006
Published online: February 19, 2007
Issue release date: May 2007

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: http://www.karger.com/CRD


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