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Table of Contents
Vol. 22, No. 4, 2007
Issue release date: June 2007
Section title: Paper
Fetal Diagn Ther 2007;22:277–281
(DOI:10.1159/000100790)

The Fetal Dandy Walker Complex: Associated Anomalies, Perinatal Outcome and Postnatal Imaging

Harper T. · Fordham L.A. · Wolfe H.M.
Departments of aObstetrics and Gynecology and bRadiology, University of North Carolina at Chapel Hill, Chapel Hill, N.C., USA

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Article / Publication Details

First-Page Preview
Abstract of Paper

Received: 1/6/2006
Accepted: 6/19/2006
Published online: 3/16/2007

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 4

ISSN: 1015-3837 (Print)
eISSN: 1421-9964 (Online)

For additional information: http://www.karger.com/FDT

Abstract

Objective: This study compares the diagnostic accuracy of prenatal ultrasound with postnatal imaging and evaluates for associated fetal anomalies and their impact on immediate neonatal outcome in fetal Dandy Walker complex (DWC). Methods: Cases of fetal DWC diagnosed in a single ultrasound unit from January 2000 through July 2004 were reviewed for associated fetal anomalies, fetal karyotype, immediate neonatal outcome and postnatal head imaging. Results: A total of 55 fetuses with DWC were identified. Of liveborn cases, postnatal imaging confirmed prenatal intracranial findings in 50% of Dandy Walker variant (DWV) and 100% of Dandy Walker malformation (DWM), with additional central nervous system findings noted in 21% of all cases. Additional fetal anomalies were seen in 26/40 (65%) cases of DWV and 15/15 (100%) cases of DWM. Immediate neonatal survival was predicted by karyotype and associated fetal anomalies. Conclusion: The sonographic diagnosis of fetal DWM is accurate. Significant discrepancies exist in prenatal and postnatal diagnosis of DWV. Comprehensive fetal ultrasound and karyotype should be offered for all fetuses with DWC. Postnatal imaging should be performed on all fetal DWC.


Article / Publication Details

First-Page Preview
Abstract of Paper

Received: 1/6/2006
Accepted: 6/19/2006
Published online: 3/16/2007

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 4

ISSN: 1015-3837 (Print)
eISSN: 1421-9964 (Online)

For additional information: http://www.karger.com/FDT


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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