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Table of Contents
Vol. 215, No. 3, 2007
Issue release date: September 2007
Section title: Case Report
Dermatology 2007;215:256–259
(DOI:10.1159/000106586)

Dermoscopic Appearance of Juvenile Xanthogranuloma

Palmer A. · Bowling J.
Department of Dermatology, Churchill Hospital, Oxford, UK

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 11/6/2006
Accepted: 4/9/2007
Published online: 9/12/2007

Number of Print Pages: 4
Number of Figures: 4
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Juvenile xanthogranuloma (JXG) is the commonest form of non-Langerhans cell histiocytosis and manifests as asymptomatic yellow-red papulonodules that usually occur in childhood and spontaneously regress within a year of formation. The diagnosis may be made by clinical examination alone and confirmed by histology in cases of diagnostic doubt. Here we report the use of dermoscopy in evaluating skin lesions suggestive of JXG. Three patients diagnosed as having JXG in our dermatology department over the last year showed a characteristic orange-yellow ‘setting sun’ appearance on dermoscopy. We therefore feel that the use of dermoscopy can be extended to include the examination of non-pigmented skin lesions, particularly in paediatric patients.


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 11/6/2006
Accepted: 4/9/2007
Published online: 9/12/2007

Number of Print Pages: 4
Number of Figures: 4
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Dehner LP: Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations. Am J Surg Pathol 2003;27:579–593.
  2. Janssen D, Harms D: Juvenile xanthogranuloma in childhood and adolescence. Am J Surg Pathol 2005;29:21–28.
  3. Saad N, Skowron F, Dalle S, et al: Multiple adult xanthogranuloma: case report and literature review. Dermatology 2006;212:73–76.
  4. Lazova R, Shapiro PE: Juvenile xanthogranuloma versus Langerhans cell histiocytosis. Semin Cutan Med Surg 1999;18:71–77.
  5. Sonoda T, Hashimoto H, Enjoji M: Juvenile xanthogranuloma: clinicopathologic analysis and immunohistochemical study of 57 patients. Cancer 1985;56:2280–2286.
  6. Zalaudek I, Argenziano G, Di Stefani A, et al: Dermoscopy in general dermatology. Dermatology 2006;212:7–18.
  7. Zaballos P, Ara M, Puig S, Malvahy J: Dermoscopy of sebaceous hyperplasia. Arch Dermatol 2005;141:808.