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Vol. 215, No. 3, 2007
Issue release date: September 2007

Dermoscopic Appearance of Juvenile Xanthogranuloma

Palmer A. · Bowling J.
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Abstract

Juvenile xanthogranuloma (JXG) is the commonest form of non-Langerhans cell histiocytosis and manifests as asymptomatic yellow-red papulonodules that usually occur in childhood and spontaneously regress within a year of formation. The diagnosis may be made by clinical examination alone and confirmed by histology in cases of diagnostic doubt. Here we report the use of dermoscopy in evaluating skin lesions suggestive of JXG. Three patients diagnosed as having JXG in our dermatology department over the last year showed a characteristic orange-yellow ‘setting sun’ appearance on dermoscopy. We therefore feel that the use of dermoscopy can be extended to include the examination of non-pigmented skin lesions, particularly in paediatric patients.



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References

  1. Dehner LP: Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations. Am J Surg Pathol 2003;27:579–593.
  2. Janssen D, Harms D: Juvenile xanthogranuloma in childhood and adolescence. Am J Surg Pathol 2005;29:21–28.
  3. Saad N, Skowron F, Dalle S, et al: Multiple adult xanthogranuloma: case report and literature review. Dermatology 2006;212:73–76.
  4. Lazova R, Shapiro PE: Juvenile xanthogranuloma versus Langerhans cell histiocytosis. Semin Cutan Med Surg 1999;18:71–77.
  5. Sonoda T, Hashimoto H, Enjoji M: Juvenile xanthogranuloma: clinicopathologic analysis and immunohistochemical study of 57 patients. Cancer 1985;56:2280–2286.
  6. Zalaudek I, Argenziano G, Di Stefani A, et al: Dermoscopy in general dermatology. Dermatology 2006;212:7–18.
  7. Zaballos P, Ara M, Puig S, Malvahy J: Dermoscopy of sebaceous hyperplasia. Arch Dermatol 2005;141:808.


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