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Table of Contents
Vol. 10, No. 4, 1991
Issue release date: 1991
Section title: Paper
Neuroepidemiology 1991;10:174–184
(DOI:10.1159/000110267)

Risk Factors in Motor Neuron Disease: A Case-Control Study

Chiò A. · Meineri P. · Tribolo A. · Schiffer D.
Second Department of Neurology, University of Turin, Italy

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 9/11/1991

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: http://www.karger.com/NED

Abstract

A case-control study of risk factors in 512 cases of motor neuron disease (MND) and 512 controls, affected by other neurological diseases, was performed. Clinical history showed a significant increase in gastric ulcer and mechanical injuries among MND cases, whereas the frequencies of operations, poliomyelitis, malignancies and autoimmune diseases were similar for cases and controls. The women affected by MND had a later menarche and an earlier menopause; therefore, the reproductive period was significantly shorter, supporting a possible role of sexual hormones in the pathogenesis of MND. The analysis of occupations showed an increased number of farmers and also of subjects exposed to chemical products among MND cases.


Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 9/11/1991

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: http://www.karger.com/NED


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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