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Vol. 51, No. 5, 2007
Issue release date: December 2007
Ann Nutr Metab 2007;51:471–476

Prevalence of Hypertension and Association of Dietary Mineral Intake with Blood Pressure in Healthy Schoolchildren from Northern Greece Aged 7–15 Years

Papandreou D. · Stamou M. · Malindretos P. · Rousso I. · Mavromichalis I.
a2nd Pediatric Department and b1st Medical Department, Renal Unit, Aristotle University of Thessaloniki, School of Medicine, AHEPA Hospital, Thessaloniki, Greece

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Background and Aims: Pediatric hypertension is urgently increasing in Greece. The purpose of this study is to record the prevalence of hypertension in schoolchildren and to relate dietary minerals to blood pressure (BP). Methods and Results: 308 males and 298 females, aged 7–15 years, from 10 schools in Northern Greece participated in the study. BP and dietary minerals were measured in all children. Twenty-seven and 12.3% of boys and 21.2 and 15.1% of girls were diagnosed with prehypertension systolic BP and systolic hypertension, respectively. For diastolic BP, 19 and 13.3% of boys and 21.5 and 15.1% of girls were diagnosed with prehypertension diastolic BP and diastolic hypertension, respectively. Systolic BP was significantly positively associated with age (β: 0.283, 95% CI: 1.440–2.484, p < 0.001), BMI (β: 0.267, 95% CI: 0.830–1.489, p < 0.001) and potassium (β: 0.139, 95% CI: 0.001–0.005, p < 0.001) and negatively related to Ca (β: –0.160, 95% CI: –0.012 to 0.002, p = 0.007). Diastolic BP was positively related only to BMI (β: 0.194, 95% CI: 0.380–0.968, p < 0.001). Conclusion: The current study tried to estimate the prevalence of hypertension among children in Northern Greece. Early prevention through nutrition education programs on BP that include diet and exercise modifications is urgently needed in order to avoid certain chronic risk factors in early life.

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  1. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr; National Heart, Lung, and Blood Institutes Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordination Committee: The seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003;289:2560–2572.
  2. Hanevold C, Waller J, Daniels S, Portman R, Sorof J; International Pediatric Hypertension Association: The effects of obesity, gender, and ethnic group on left ventricular hypertrophy and geometry in hypertensive children: a collaborative study of the International Pediatric Hypertension Association. Pediatrics 2004;113:328–333.
  3. National Heart, Lung and Blood Institute, National Institutes of Health: Update on the task force report (1987) on high blood pressure in children and adolescents: a working group report from the National High Blood Pressure Program. Pediatrics 1996;98:649–658.

    External Resources

  4. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents: The fourth report on the diagnosis, evaluation and treatment of high blood pressure in children and adolescents. Pediatrics 2004;114:555–576.
  5. Barba G, Troiano E, Russo P, Strazzullo P, Siani A: Body mass, fat distribution and blood pressure in Southern Italian children: results of the ARCA project. Nutr Metab CardiovascDis 2006;16:239–248.
  6. Graf C, Rost SV, Koch B, Heinen S, Falkowski G, Dordel S, et al:Data from the StEP TWO programme showing the effect on blood pressure and different parameters for obesity in overweight and obese primary school children. CardiolYoung 2005;15:291–298.
  7. Townsend MS, Fulgoni VL III, Stern JS, Adu-Afarwuah S, McCarron DA: Low mineral intake is associated with high systolic blood pressure in the Third and Fourth National Health and Nutrition Examination Surveys: could we all be right? Am J Hyperten 2005;18:261–269.
  8. Angelopoulos PD, Milionis HJ, Moschonis G, Manios Y: Relations between obesity and hypertension: preliminary data from a cross-sectional study in primary schoolchildren: the children study. Eur J Clin Nutr 2006;60:1226–1234.
  9. Kafatos I, Manios Y, Moschandreas J, Kafatos A: Health and nutrition education program in primary schools of Crete: changes in blood pressure over 10 years. Eur J Clin Nutr 2007;61:837–845.
  10. Magkos F, Manios Y, Christakis G, Kafatos AG: Secular trends in cardiovascular risk factors among school-aged boys from Crete, Greece, 1982–2002. Eur J Clin Nutr 2005;59:1–7.
  11. Mamalakis G, Kafatos A, Manios Y, Anagnostopoulou T, Apostolaki I: Obesity indices in a cohort of primary school children in Crete: a six year prospective study. Int J Obes Relat Metab Disord 2000;24:765–771.
  12. Cole JT, Bellizzi CM, Flegal MK, Dietz WH: Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000;320:1240–1247.
  13. Netea RT, Lenders JW, Smits P, Thien T: Both body and arm position significantly influence blood pressure measurement. J Hum Hypertens 2003;17:459–462.
  14. Trichopoulou A: Composition tables of foods and Greek dishes. Athens, Greece, Department of Hygiene and Epidemiology, School of Medicine, 2004.
  15. Obesity: preventing and managing the global epidemic: report of a WHO consultation. World Health Organ Tech Rep Ser 2000;i–xii:1–253.
  16. Chimonas ET: The treatment of coronary heart disease: an update. Part 2. Mortality trends and main causes of death in the Greek population. Curr MedRes Opin 2001;17:27–33.
  17. Lauer RM, Anderson AR, Beaglehole R, Burns TL: Factors related to tracking of blood pressure in children. US National Center for Health Statistics, Health Examination Surveys Cycle II and III. Hypertension 1984;6:307–314.
  18. Report of the Second Task Force on blood pressure control in children. Task Force on Blood Pressure Control in Children. National Heart, Lung, and Blood Institute, Bethesda, Maryland. Pediatrics 1987;79:1–25.
  19. Menghetti E, Virdis R, Strambi M, Patriarca V, Riccioni MA, Fossali E, Spagnolo A: Blood pressure in childhood and adolescence: the Italian normal standards. Study Group on Hypertension of the Italian Society of Pediatrics. JHypertens 1999;17:1363–1372.
  20. Moreira P, Padez C, Mourao I, Rosado V: Dietary calcium and body mass index in Portuguese children. Euro J Clin Nutr 2005;59:861–867.
  21. Manios Y, Yiannakouris M, Papoutsakis C, Moschonis G, Magkos F, Skenderi M: Behavioral and physiological indices related to BMI in a cohort of primary schoolchildren in Greece. Am J Hum Biol 2004;16:639–647.
  22. Matheson DM, Killen JD, Wang Y, Varady A, Robinson TN: Children’s food consumption during television viewing. Am J Clin Nutr 2004;79:1088–1094.
  23. Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM: A clinical trial of the effects of dietary patterns on blood pressure. N Engl J Med 1997;336:1117–1124.
  24. Franco V, Oparil S: Salt sensitivity, a determinant of blood pressure, cardiovascular disease and survival. J Am Coll Nutr 2006;25:247S–255S.
  25. Svetkey LP, Simons-Morton DG, Proschan MA, Sacks FM, Conlin PR, Harsha D: Effect of the dietary approaches to stop hypertension diet and reduced sodium intake on blood pressure control. J Clin Hypertens 2004;6:373–381.

    External Resources

  26. Dickinson HO, Nicolson DJ, Campbell F, Beyer FR, Mason J: Potassium supplementation for the management of primary hypertension in adults. Cochrane Database Syst Rev 2006;19:CD004641.
  27. Daniel EE: Intake of dairy products or calcium and blood pressure. J Hypertens 2006;24:633–634.
  28. Barba G, Russo R: Dairy foods, dietary calcium and obesity: a short review of the evidence. Nutr Metab Cardiovasc Dis 2006;16:455–451.

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