- Family-based analysis
- High-risk pedigrees
A unique genealogical resource linked to phenotype data was created in Utah over 30 years ago. Here we review the history and content of this resource. In addition, we review three current methodologies used in conjunction with this resource to define the heritable contribution to phenotypes and to identify predisposition genes responsible for these phenotypes. Example analyses and high-risk pedigrees are presented. Finally we briefly review ways this resource, or others like it, may expand in future.
Copyright © 2007 S. Karger AG, Basel
Lisa A. Cannon Albright, PhD
Division of Genetic Epidemiology
391 Chipeta Way, Suite D
Salt Lake City, UT 84108 (USA)
Tel. +1 801 587 9300, Fax +1 801 581 6052, E-Mail firstname.lastname@example.org
Received: April 20, 2007
Accepted after revision: July 30, 2007
Published online: Decembre 11, 2007
Number of Print Pages : 12
Number of Figures : 6, Number of Tables : 6, Number of References : 42
Human Heredity (International Journal of Human and Medical Genetics)
Vol. 65, No. 4, Year 2008 (Cover Date: January 2008)
Journal Editor: Devoto, M. (Philadelphia, Pa.)
ISSN: 0001–5652 (Print), eISSN: 1423–0062 (Online)
For additional information: http://www.karger.com/HHE
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