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Vol. 30, No. 1, 2008
Issue release date: March 2008
Neuroepidemiology 2008;30:25–33

Prevalence and Pattern of Cognitive Impairment in a Community Cohort of Men in South Wales: Methodology and Findings from the Caerphilly Prospective Study

Fish M. · Bayer A.J. · Gallacher J.E.J. · Bell T. · Pickering J. · Pedro S. · Dunstan F.D. · Ben-Shlomo Y. · Ebrahim S.
aDepartments of Geriatric Medicine and Neurology, and bDepartment of Epidemiology, Statistics and Public Health, Centre for Health Sciences Research, Cardiff University, Cardiff, cDepartment of Social Medicine, University of Bristol, Bristol, and dLondon School of Hygiene and Tropical Medicine, London, UK

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Background/Aims: The prevalence of dementia and cognitive impairment not dementia was investigated in the Caerphilly Prospective Study cohort (men currently aged 65–84 years). Methods: Of 1,633 men eligible for cognitive screening, 1,225 (75%) were seen, with those failing the screening criteria (CAMCOG <83 or decline in CAMCOG >9) being neurologically examined. Results: For dementia, diagnosed by DSM-IV criteria, the population prevalence was 5.2% rising to 6.1% in the screened population. For cognitive impairment not dementia, the prevalence in the screened population was 15.6% giving an overall prevalence of cognitive impairment of 21.8%. Prevalence rose fivefold between ages of 65 and 84 years to reach over 50%. Conclusion: These figures are likely to underestimate actual prevalence in this population, and developing effective interventions should be a public health priority.

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