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Table of Contents
Vol. 25, No. 1, 2008
Issue release date: April 2008
Section title: Original Paper
Dig Surg 2008;25:39–45
(DOI:10.1159/000117822)

A Systematic Review of the Efficacy of Gum Chewing for the Amelioration of Postoperative Ileus

de Castro S.M.M. · van den Esschert J.W. · van Heek N.T. · Dalhuisen S. · Koelemay M.J.W. · Busch O.R.C. · Gouma D.J.
aAcademic Medical Center of the University of Amsterdam, and bTergooi Hospital, Hilversum, The Netherlands

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 3/5/2007
Accepted: 9/12/2007
Published online: 2/21/2008

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: http://www.karger.com/DSU

Abstract

Background: Recent trials have shown promising results for the efficacy of gum chewing for the amelioration of postoperative ileus. This finding could have a major clinical impact since gum chewing is relatively harmless and cheap while postoperative ileus has a significant impact on healthcare. Methods: Systematic review and meta-analysis of randomized controlled trials comparing the efficacy of gum chewing after colorectal surgery to a standard control for the amelioration of postoperative ileus, expressed as time to flatus, time to defecation and overall hospital stay. Results: Five randomized controlled trials with a total number of 158 patients were found. The studies were homogeneous and a meta-analysis was performed. The pooled weighted mean difference (WMD) of time to flatus was significantly shorter for the gum-chewing group (20 h with a 95% confidence interval (CI) of 13–27). The pooled WMD of time to defecation was significantly shorter (29 h, 95% CI of 19–39). There was a non-significant trend towards a shorter postoperative hospital stay (1.3 days shorter, 95% CI of 3.2 days shorter to 0.6 days longer). Conclusion: This meta-analysis shows a favorable effect of gum chewing on time to flatus and defecation but no significant effect on the hospital stay.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 3/5/2007
Accepted: 9/12/2007
Published online: 2/21/2008

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: http://www.karger.com/DSU


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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