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Table of Contents
Vol. 56, No. 3, 1999
Issue release date: April 1999
Section title: Clinical Study
Oncology 1999;56:189–192
(DOI:10.1159/000011963)

Gross Pathologic Types of Hepatocellular Carcinoma in Italy

Stroffolini T. · Andreone P. · Andriulli A. · Ascione A. · Craxì A. · Chiaramonte M. · Galante D. · Manghisi O.G. · Mazzanti R. · Medaglia C. · Pilleri G. · Rapaccini G.L. · Albanese M. · Taliani G. · Tosti M.E. · Villa E. · Gasbarrini G.
aLaboratorio di Epidemiologia, ISS, Roma, bIstituto di Patologia Medica, University of Bologna, cDepartment of Gastroenterology, IRCCS. S. Giov. Rotondo Hospital, Sangiovanni Rotondo, dDepartment of Gastroenterology, Cardarelli Hospital Napoli, eIstituto di Medicina Interna, University of Palermo, fDivisione Gastroenterologia, University of Padova, gClinica Malattie Infettive, University of Napoli, hDepartment of Gastroenterology, Castellana Grotte Hospital, Castellana Grotte, iIstituto di Clinica Medica, University of Firenze, jIstituto di Medicina Interna, IRCCS Maggiore Hospital, Milano, kDepartment of Internal Medicine, Cagliari Hospital, Cagliari, lClinica Medica, Policlinico Gemelli, University of Rome, mClinica Medica R, University of Palermo, nClinica Malattie Tropicali, University of Rome, and oDivisione Gastroenterologia, University of Modena, Italy

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Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Published online: 4/8/1999

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3

ISSN: 0030-2414 (Print)
eISSN: 1423-0232 (Online)

For additional information: http://www.karger.com/OCL

Abstract

The prevalence and independent predictors of the different macroscopic types of hepatocellular carcinoma (HCC) were assessed in 1,073 unselected patients of 14 hospitals in Italy from May 1996 to May 1997. Solitary HCC was the most common cancer type (44.6%), followed by multinodular (44.2%), diffuse (8.4%) and massive (2.8%) types. After adjustment for the influence of confounders by multiple logistic regression analysis, Child-Pugh grades B and C were found to be independent predictors of multinodular (odds ratio, OR, 2.0; 95% confidence interval (CI) = 1.5–2.6) and diffuse (OR 2.6; 95% CI = 1.6–4.4) HCC types. These findings indicate that the majority of HCC cases are not detected at a potentially treatable stage. Delayed detection of HCC is associated with a higher likelihood of the multinodular or diffuse gross pathologic type.


Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Published online: 4/8/1999

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3

ISSN: 0030-2414 (Print)
eISSN: 1423-0232 (Online)

For additional information: http://www.karger.com/OCL


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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