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Vol. 57, No. 1-2, 2008
Issue release date: June 2008
Section title: Original Paper
Neuropsychobiology 2008;57:26–31
(DOI:10.1159/000123119)

Tobacco Smoking and Depression – Results from the WHO/ISBRA Study

Wiesbeck G.A. · Kuhl H.-C. · Yaldizli Ö. · Wurst F.M.
aPsychiatric University Clinics, Basel, Switzerland; bChristian-Doppler-Clinic, Paracelsus Medical University, Salzburg, Austria

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 9/5/2007
Accepted: 1/25/2008
Published online: 4/18/2008

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 4

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: http://www.karger.com/NPS

Abstract

Aims: To elucidate the relationship between tobacco smoking and depression, and to estimate the impact of other substance dependencies. Design: Cross-sectional. Participants: A total of 1,849 men and women were interviewed face-to-face using a validated structured questionnaire. According to their tobacco smoking behavior, participants were grouped into never smokers, ex-smokers and current smokers. Measurements: Data were generated through the WHO/ISBRA study, an international multicenter study with a cross-sectional design. A standardized questionnaire was administered face-to-face by trained interviewers. Logistic regression analysis was used to predict depression. Results: There was a significant difference across the 3 smoking groups in the number of subjects who had major depression (DSM-IV) during their lifetime. The highest rate of depressives was found in current smokers (23.7%), the lowest rate in never smokers (6.2%), while the rate of those who had quit smoking (14.6%) was between both. In a logistic regression analysis, alcohol dependence (both current and during lifetime) as well as cocaine dependence were significant predictors of depression. However, the association between smoking and depression still remained statistically significant. Conclusions: This study adds support to the evidence that smoking is linked to depression. It also elucidates the importance of taking into account alcohol and cocaine dependence since they have a significant impact on the relationship between smoking and depression.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 9/5/2007
Accepted: 1/25/2008
Published online: 4/18/2008

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 4

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: http://www.karger.com/NPS


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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References

  1. Wu LT, Anthony JC: Tobacco smoking and depressed mood in late childhood and early adolescence. Am J Public Health 1999;89:1837–1840.
  2. Goodman E, Capitman J: Depressive symptoms and cigarette smoking among teens. Pediatrics 2000;106:748–755.
  3. Breslau N, Peterson EL, Schultz LR, Chilcoat HD, Andreski P: Major depression and stages of smoking: a longitudinal investigation. Arch Gen Psychiatry 1998;55:161–166.
  4. Breslau N, Kilbey MM, Andreski P: Nicotine dependence and major depression: new evidence from a prospective investigation. Arch Gen Psychiatry 1993;50:31–35.
  5. Choi WS, Patten CA, Gillin JC, Kaplan RM, Pierce JP: Cigarette smoking predicts development of depressive symptoms among US adolescents. Ann Behav Med 1997;19:42–50.
  6. Martini S, Wagner FA, Anthony JC: The association of tobacco smoking and depression in adolescence: evidence from the United States. Subst Use Misuse 2002;37:1853–1867.
  7. Murphy JM, Horton NJ, Monson RR, Laird NM, Sobol AM, Leighton AH: Cigarette smoking in relation to depression: historical trends from the Stirling County Study. Am J Psychiatry 2003;160:1663–1669.
  8. Killen JD, Robinson TN, Ammerman S, Hayward C, Rogers J, Samuels D, Schatzberg AF: Major depression among adolescent smokers undergoing treatment for nicotine dependence. Addict Behav 2004;29:1517–1526.
  9. Fergusson DM, Goodwin RD, Horwood LJ: Major depression and cigarette smoking: results of a 21-year longitudinal study. Psychol Med 2003;33:1357–1367.
  10. Glassman AH, Covey LS, Stetner F, Rivelli S: Smoking cessation and the course of major depression: a follow-up study. Lancet 2001;357:1929–1932.
  11. Almeida OP, Pfaff JJ: Depression and smoking amongst older general practice patients. J Affect Disord 2005;86:317–321.
  12. Breslau N, Schultz LR, Johnson EO, Peterson EL, Davis GC: Smoking and the risk of suicidal behavior: a prospective study of a community sample. Arch Gen Psychiatry 2005;62:328–334.
  13. Hemmingsson T, Kriebel D: Smoking at age 18–20 and suicide during 26 years of follow-up: how can the association be explained? Int J Epidemiol 2003;32:1000–1004.
  14. Wang Y, Browne DC, Storr CL, Wagner FA: Gender and the tobacco-depression relationship: a sample of African American college students at a historically black college or university (HBCU). Addict Behav 2005;30:1437–1441.
  15. Steuber TL, Danner F: Adolescent smoking and depression: which comes first? Addict Behav 2005;31:133–136.

    External Resources

  16. Karam-Hage M, Pomerleau CS, Pomerleau OF, Brower KJ: Unaided smoking cessation among smokers in treatment for alcohol dependence. Addict Behav 2005;30:1247–1253.
  17. Anda RF, Williamson DF, Escobedo LG, Mast EE, Giovino GA, Remington PL: Depression and the dynamics of smoking: a national perspective. JAMA 1990;264:1583–1584.

    External Resources

  18. Winkleby MA, Feighery E, Dunn M, Kole S, Ahn D, Killen JD: Effects of an advocacy intervention to reduce smoking among teenagers. Arch Pediatr Adolesc Med 2004;158:269–275.
  19. Hitsman B, Borrelli B, McChargue DE, Spring B, Niaura R: History of depression and smoking cessation outcome: a meta-analysis. J Consult Clin Psychol 2003;71:657–663.
  20. Glanz J, Grant B, Monteiro M, Tabakoff B, WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence Investigators: WHO/ISBRA study on state and trait markers of alcohol use and dependence: analysis of demographic, behavioral, physiologic, and drinking variables that contribute to dependence and seeking treatment. Alcohol Clin Exp Res 2002;26:1047–1061.
  21. Berlin I, Anthenelli RM: Monoamine oxidases and tobacco smoking. Int J Neuropsychopharmacol 2001;4:33–42.
  22. Snell LD, Glanz J, Tabakoff B, WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence Investigators: Relationships between effects of smoking, gender, and alcohol dependence on platelet monoamine oxidase-B: activity, affinity labeling, and protein measurements. Alcohol Clin Exp Res 2002;26:1105–1113.
  23. Wiesbeck GA, Wodarz N, Weijers H-G, Dürsteler-MacFarland KM, Wurst FM, Walter M, Boening J: A functional polymorphism in the promoter region of the monoamine oxidase A gene is associated with the cigarette smoking quantity in alcohol-dependent heavy smokers. Neuropsychobiology 2006;53:181–185.
  24. Balfour D, Ridley D: The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction? Pharmacol Biochem Behav 2000;66:79–85.
  25. Anthony JC, Echeagaray-Wagner F: Epidemiologic analysis of alcohol and tobacco use. Alcohol Res Health 2000;24:201–208.
  26. Romberger DJ, Grant K: Alcohol consumption and smoking status: the role of smoking cessation. Biomed Pharmacother 2004;58:77–83.
  27. Klungsøyr O, Nygård JF, Sørensen T, Sandanger I: Cigarette smoking and incidence of first depressive episode: an 11-year population-based follow-up study. Am J Epidemiol 2006;163:421–432.