Journal Mobile Options
Table of Contents
Vol. 217, No. 1, 2008
Issue release date: June 2008
Dermatology 2008;217:66–68

Lentigo Maligna in a Young Adult

Ferrara G. · Ligrone L. · Zalaudek I. · Mordente I. · Argenziano G.
aPathologic Anatomy Unit, Gaetano Rummo General Hospital, Benevento, bDermatology Unit, S. Maria della Speranza Hospital, Battipaglia, Italy; cDepartment of Dermatology, Medical University of Graz, Graz, Austria; dDepartment of Dermatology, Second University of Naples, Naples, Italy

Individual Users: Register with Karger Login Information

Please create your User ID & Password

Contact Information

I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in


Background: Lentigo maligna is mainly diagnosed in the elderly with severely sun-damaged skin. Observation: We describe a case of lentigo maligna in a 51-year-old woman with Fitzpatrick skin type III. Based on private photographs of the patient, we were able to ascertain that the lesion was already present at the age of 22 years. Despite the 29-year clinical history, the lesion was still entirely intraepidermal on histologic examination. Conclusion: Lentigo maligna in young adults is extremely rare, and therefore represents a diagnostic challenge for both clinicians and histopathologists.

Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.


  1. Cohen LM: Lentigo maligna and lentigo maligna melanoma. J Am Acad Dermatol 1995;33:923–936.
  2. Grinspan D, Abulafia J: Lentigo maligno de Hutchinson (melanosis circunscrita precancerosa de Dubreuilh): caracteres clínicos, histopatológicos y diagnóstico diferencial. Arch Argent Dermatol 1956;6:351–387.
  3. Holman CDJ, Armstrong BK: Cutaneous malignant melanoma and indicators of total accumulated exposure to the sun: an analysis separating histogenetic types. J Natl Cancer Inst 1984;73:75–82.
  4. Durnick A, Stolz W, Landthaler M, Vogt T: Lentigo maligna and lentigo maligna in young adults. Dermatol Surg 2004;30:813–816.
  5. Weedon D: Lentigines, nevi and melanomas; in Weedon D (ed): Skin Pathology. Edinburgh, Churchill Livingstone, 2002, pp 803–858.
  6. Weinstock MA, Sober AJ: The risk of progression of lentigo maligna to lentigo maligna melanoma. Br J Dermatol 1987;116:303–310.
  7. Bevona C, Fewkes J, Liu V, Sober AJ: Prolonged evolution of a lentigo maligna. J Am Acad Dermatol 2004;51:830–835.

Pay-per-View Options
Direct payment This item at the regular price: USD 33.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 23.00