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Vol. 28, No. 3, 1980
Issue release date: 1980
Cytogenet Cell Genet 1980;28:169–172

Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22

Geurts van Kessel A.H.M. · Westerveld A. · de Groot P.G. · Meera Khan P. · Hagemeijer A.
aDepartment of Cell Biology and Genetics, Erasmus University, Rotterdam, bLaboratory of Biochemistry, B.C.P. Jansen Institute, University of Amsterdam, and cDepartment of Human Genetics, University of Leiden

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The segregation of the chromosome 22 markers AC02, ARSA, and NAGA was studied in somatic cell hybrid clones. These hybrids were isolated following fusion of Chinese hamster (E36 or a3) cells with leucocytes of donors carrying an (X;22) or (1;22) translocation. The results suggest the assignment of ARSA and NAGA to the region 22q13→22qter and of AC02 to the region 22q11→22q13.

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