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Table of Contents
Vol. 11, No. 6, 2008
Issue release date: August 2008
Section title: Original Paper
Community Genet 2008;11:331–342
(DOI:10.1159/000133305)

Population Estimates of Extended Family Structure and Size

Garceau A. · Wideroff L. · McNeel T. · Dunn M. · Graubard B.I.
aDivision of Cancer Control and Population Sciences, Risk Factor Monitoring and Methods Branch, and bDivision of Cancer Epidemiology and Genetics, Biostatistics Branch, National Cancer Institute, Bethesda, Md., cInformation Management Services Inc., Silver Spring, Md., and dWestat Inc., Rockville, Md., USA

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 8/5/2008

Number of Print Pages: 12
Number of Figures: 4
Number of Tables: 4

ISSN: 1662-4246 (Print)
eISSN: 1662-8063 (Online)

For additional information: http://www.karger.com/PHG

Abstract

Background: Population-based estimates of biological family size can be useful for planning genetic studies, assessing how distributions of relatives affect disease associations with family history and estimating prevalence of potential family support. Methods: Mean family size per person is estimated from a population-based telephone survey (n = 1,019). Results: After multivariate adjustment for demographic variables, older and non-White respondents reported greater mean numbers of total, first- and second-degree relatives. Females reported more total and first-degree relatives, while less educated respondents reported more second-degree relatives. Conclusions: Demographic differences in family size have implications for genetic research. Therefore, periodic collection of family structure data in representative populations would be useful.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 8/5/2008

Number of Print Pages: 12
Number of Figures: 4
Number of Tables: 4

ISSN: 1662-4246 (Print)
eISSN: 1662-8063 (Online)

For additional information: http://www.karger.com/PHG


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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