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Vol. 66, No. 3, 1994
Issue release date: 1994
Cytogenet Cell Genet 1994;66:162–163

Assignment of the human cytokeratin 3 gene (KRT3) to 12q12→q13 by FISH

Raimondi E. · Moralli D. · De Carli L. · Ceratto N. · Balzaretti M. · Leube R. · Collin C. · Romano V.
aDipartimento di Genetica e Microbiologia “A. Buzzati Traverso,” Università di Pavia, Pavia (Italy); bLaboratorio di Genetica Molecolare, Oasi Istituto per la Ricerca sul Ritardo Mentale e l’Involuzione Cerebrale (IRCCS), Troina (EN) (Italy); and cInstitute of Cell and Tumor Biology, Deutsches Krebsforschungszentrum, Heidelberg (Germany)

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We used fluorescence in situ hybridization to localize the human gene for cytokeratin 3 (KJRT3), a member of the type II subfamily of cytokeratins, within the human genome. The results show that KRT3 is located within chromosome region 12q12→q13. All human type II keratin genes mapped to date have been assigned to chromosome 12, where they are likely to be organized into one homotypic cluster.

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