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Table of Contents
Vol. 68, No. 3-4, 1995
Issue release date: 1995
Cytogenet Cell Genet 1995;68:231–232
(DOI:10.1159/000133919)

The human OTF1 locus which overlaps the CD3Z gene is located at 1q22→q23

Sturm R.A. · Eyre H.J. · Baker E. · Sutherland G.R.
aCentre for Molecular Biology and Biotechnology, The University of Queensland, Brisbane (Australia); and bCentre for Medical Genetics, Department of Cytogenetics and Molecular Genetics, Women’s and Children’s Hospital, North Adelaide (Australia)

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Abstract

The human OTF1 locus encoding the Oct-1 protein has previously been mapped to chromosome 1cen→q32 by analysis of somatic cell hybrids. We report here the regional localization of OTF1 to 1q22→q23 by fluorescence in situ hybridization. The physical linkage of the CD3Z gene to the OTF1 transcription unit also refines the location of the CD3Z locus to 1q22→q23.



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