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Extreme Hyperphosphatemia and Acute Renal Failure after a Phosphorus-Containing Bowel Regimen

Orias M. · Mahnensmith R.L. · Perazella M.A.
Section of Nephrology, Yale University School of Medicine, New Haven, Conn., USA Am J Nephrol 1999;19:60–63 (DOI:10.1159/000013427)


Phosphate intoxication, manifested by hypocalcemic tetany and acute renal failure, may complicate bowel-cleansing preparations which contain phosphate. These preparations are commonly used to prepare patients for various gastrointestinal procedures. Often, patients who receive these regimens are at increased risk of phosphate intoxication from diseases which slow gastrointestinal transit or decrease renal excretion (renal insufficiency). We present a patient who developed oliguric acute renal failure from severe phosphate intoxication associated with a phosphate-containing bowel-cleansing regimen.


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