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Vol. 73, No. 1-2, 1996
Issue release date: 1996
Cytogenet Cell Genet 1996;73:97–98
(DOI:10.1159/000134316)

The human gene encoding the heavy chain of the major histocompatibility complex class I-like Fc receptor (FCGRT) maps to 19q13.3

Kandil E. · Egashira M. · Miyosi O. · Niikawa N. · Ishibashi T. · Kasahara M.
aDepartment of Biochemistry, Hokkaido University School of Medicine, Sapporo, and Departments of bHuman Genetics and cOrthopedics, Nagasaki University School of Medicine, Nagasaki (Japan)

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Abstract

FcRn is an Fc receptor that structurally resembles the major histocompatibility complex class I molecule. In this study, we isolated the human gene encoding the heavy chain of FcRn (FCGRT) and mapped it by fluorescence in situ hybridization to chromosome band 19q13.3. Thus, like its mouse counterpart, the human FCGRT gene is located outside the major histocompatibility complex.



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