Vitalism and Synthesis of Urea
From Friedrich Wöhler to Hans A. KrebsKinne-Saffran E. · Kinne R.K.H.
Max-Planck-Institut für molekulare Physiologie, Dortmund, Germany Am J Nephrol 1999;19:290–294 (DOI:10.1159/000013463)
In 1828, Friedrich Wöhler, a German physician and chemist by training, published a paper that describes the formation of urea, known since 1773 to be a major component of mammalian urine, by combining cyanic acid and ammonium in vitro. In these experiments the synthesis of an
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