Table of Contents
To view the fulltext, log-in or choose pay-per-view options:
Get Access

Long-Term Prognosis of Steroid-Dependent Sensorineural Hearing Loss

Kanzaki J.a, b · Kanzaki S.a · Ogawa K.a
aDepartment of Otolaryngology, Keio University, School of Medicine, Shinjuku, Tokyo, and bDepartment of Otolaryngology, International University of Health and Welfare, Atami, Japan Audiol Neurotol 2009;14:26–34 (DOI:10.1159/000151587)


We report on the long-term follow-up of 15 patients with steroid-dependent sensorineural hearing loss (SDSNHL), which was steroid dose dependent. We classified the patients into 2 groups: group A consisted of 6 patients with systemic SDSNHL, and group B consisted of 9 patients with inner-ear-specific SDSNHL without systemic disease. Group B patients were further classified as patients with slowly or rapidly progressive hearing loss. The yearly rate of hearing deterioration was greater in group B than in group A. Thus, the long-term hearing prognosis of patients in group B was worse than those in group A. Although SDSNHL may have immune-related origins, we hypothesize that hearing deterioration may be caused by proinflammatory cytokines because many of our cases exhibited abnormal immunological laboratory values and because many of these cases responded favorably to steroid treatment.


Individual Users: Register with Karger Login Information

Please create your User ID & Password

Contact Information

I have read the Karger Terms and Conditions and agree.

Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50