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Vol. 88, No. 3-4, 2000
Issue release date: 2000
Cytogenet Cell Genet 88:246–248 (2000)

The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17

Sakamaki K. · Kanda N. · Ueda T. · Aikawa E. · Nagata S.
aInstitute for Virus Research, Kyoto University, Kyoto; bDepartment of Veterinary Medicine, Tokyo University Agriculture and Technology, Tokyo; cThird Department of Internal Medicine, Osaka City University Medical School, Osaka; dDepartment of Anatomy and Developmental Biology, Tokyo Women’s Medical University, Tokyo; and eDepartment of Genetics, Osaka University Medical School, Osaka (Japan)

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Eosinophil peroxidase (EPX) is one of a family of mammalian peroxidases that includes myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Here we show that the human EPX gene maps to chromosome 17q23.1, which localizes 34 kb from the LPO and MPO genes. Our results demonstrate that the EPX, LPO, and MPO genes form a cluster on human chromosome 17.   

Copyright © 2000 S. Karger AG, Basel

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