The aim of this study was to examine the colonization of Streptococcus mutans and Streptococcus sanguinis in the oral cavity and the association with severe early childhood caries (S-ECC). Saliva and plaque samples were collected from 14 S-ECC children and 8 caries-free (CF) children. All S-ECC children were S. mutans positive; 100% of CF children and 93% of S-ECC children were S. sanguinis positive. The children’s caries severity was positively correlated with levels of S. mutans (p < 0.001), total oral streptococci (p < 0.01), total cultivable oral bacteria (p < 0.05), and children’s age (p < 0.05). Logistic regression analysis showed that the interaction of S. sanguinis with S. mutans was a significant factor associated with the caries status in children, suggesting that the relative levels of these two microorganisms in the oral cavity play an important role in caries development.
© 2008 S. Karger AG, Basel
- Early childhood caries
- Streptococcus mutans
- Streptococcus sanguinis
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Dr. Yihong Li
New York University College of Dentistry
345 E. 24th Street
New York, NY 10010-4086 (USA)
Tel. +1 212 998 9607, Fax +1 212 995 4087, E-Mail firstname.lastname@example.org
Received: November 20, 2007
Accepted after revision: August 6, 2008
Published online: October 3, 2008
Number of Print Pages : 5
Number of Figures : 0, Number of Tables : 3, Number of References : 30
Vol. 42, No. 6, Year 2008 (Cover Date: November 2008)
Journal Editor: Shellis R.P. (Bristol)
ISSN: 0008–6568 (Print), eISSN: 1421–976X (Online)
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