- Early childhood caries
- Streptococcus mutans
- Streptococcus sanguinis
The aim of this study was to examine the colonization of Streptococcus mutans and Streptococcus sanguinis in the oral cavity and the association with severe early childhood caries (S-ECC). Saliva and plaque samples were collected from 14 S-ECC children and 8 caries-free (CF) children. All S-ECC children were S. mutans positive; 100% of CF children and 93% of S-ECC children were S. sanguinis positive. The children’s caries severity was positively correlated with levels of S. mutans (p < 0.001), total oral streptococci (p < 0.01), total cultivable oral bacteria (p < 0.05), and children’s age (p < 0.05). Logistic regression analysis showed that the interaction of S. sanguinis with S. mutans was a significant factor associated with the caries status in children, suggesting that the relative levels of these two microorganisms in the oral cavity play an important role in caries development.
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Dr. Yihong Li
New York University College of Dentistry
345 E. 24th Street
New York, NY 10010-4086 (USA)
Tel. +1 212 998 9607, Fax +1 212 995 4087, E-Mail email@example.com
Received: November 20, 2007
Accepted after revision: August 6, 2008
Published online: October 3, 2008
Number of Print Pages : 5
Number of Figures : 0, Number of Tables : 3, Number of References : 30
Vol. 42, No. 6, Year 2008 (Cover Date: November 2008)
Journal Editor: Shellis R.P. (Bristol)
ISSN: 0008–6568 (Print), eISSN: 1421–976X (Online)
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