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Botulinum Toxin Type A – Treatment of a Patient with Multiple Cutaneous Piloleiomyomas

Sifaki M.K.a · Krueger-Krasagakis S.a · Koutsopoulos A.b · Evangelou G.I.a · Tosca A.D.a
Departments of aDermatology and bPathology, Faculty of Medicine, University of Crete, Heraklion, Greece Dermatology 2009;218:44–47 (DOI:10.1159/000173695)


Background: Treatment of multiple cutaneous piloleiomyomas which are rare, frequently painful, benign tumors originating from the arrector pilorum muscle of hair follicles is difficult. Objective: To determine the efficiency of botulinum toxin type A (BT-A) treatment for pain relief of cutaneous piloleiomyomas. Methods: A patient with multiple painful piloleiomyomas was treated with local injections of 200 units of BT-A. Results: There was a rapid and sustained decrease in pain. Treatment was repeated every 3 months for 2 years with the same efficacy. Conclusion: BT-A may be a promising new treatment option for multiple painful cutaneous piloleiomyomas.


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