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Table of Contents
Vol. 196, No. 1, 1998
Issue release date: 1998

Why and When the Treatment of Acne Fails

What to Do

Katsambas A.D.
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The majority of acne patients show a good response to the proper acne treatment. However, a small percentage not exceeding 10–15% do not respond as satisfactorily as expected. The main reason for the treatment failure is the poor patient compliance. In order to improve the patient compliance the strategy for the treatment of acne has to be carefully planned and includes the following: discussion before treatment; give clear instructions; explain the rhythm of improvement; explain the role of cosmetics; explain the role of sunbathing; explain the expected side effects. It has to be emphasized that all acne cases can be adequately controlled if the relationship between doctor and patient has been built on trust and confidence, maximizing the patient compliance.

Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.


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  2. Kligman AM: Acne vulgaris: Tricks and treatments. Part 1. Cutis 1995;56:141–143.
  3. Draelos K II: Patient compliance: Enhancing clinical abilities and strategies. J Am Acad Dermatol 1995;32:542–548.
  4. Cunliffe WJ: Strategy of treating acne vulgaris. J Eur Acad Dermatol Venereol 1992;1:43–52.
  5. Mills OH, Kligman AM: A human model for assessing comedogenic substances. Arch Dermatol 1983;118:903–905.

    External Resources

  6. Report of the 1998 American Academy of Dermatology Invitational Symposium on Comedogenicity. J Am Acad Dermatol 1989;30: 272–277.

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