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Table of Contents
Vol. 29, No. 5, 2009
Issue release date: April 2009
Section title: Original Report: Laboratory Investigation
Am J Nephrol 2009;29:473–482
(DOI:10.1159/000178816)

Chronic Kidney Disease and US Healthcare Resource Utilization in a Nationally Representative Sample

Alexander M. · Bradbury B.D. · Kewalramani R. · Barlev A. · Mohanty S.A. · Globe D.
aHarvard University and Beth Israel Deaconess Medical Center, Boston, Mass., bDepartment of Biostatistics and Epidemiology, Amgen Inc., cClinical Development, Amgen Inc., dGlobal Health Economics, Amgen Inc., Thousand Oaks, Calif., and eUniversity of Southern California, Keck School of Medicine, Los Angeles, Calif., USA

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Article / Publication Details

First-Page Preview
Abstract of Original Report: Laboratory Investigation

Received: 8/6/2008
Accepted: 9/4/2008
Published online: 11/27/2008

Number of Print Pages: 10
Number of Figures: 1
Number of Tables: 4

ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)

For additional information: http://www.karger.com/AJN

Abstract

Background: Chronic kidney disease (CKD) is a prevalent condition; however, little is known about healthcare resource utilization (HRU) by CKD patients. Methods: This analysis included NHANES participants aged ≥18 years, with serum creatinine, urine protein, and hemoglobin measurements. We assessed the association between CKD (stratified by stage) and HRU based on self-reported physician visits and hospitalizations in the year preceding the survey. Results: Of the 15,258 included in this analysis, 2,110 had early CKD (stage 1 and 2 CKD) and 1,121 had late CKD (stage 3 and 4 CKD). Mean (SE) number of annual physician visits were 3.51 (0.08), 4.43 (0.18), and 6.53 (0.38) for participants with no CKD, early CKD, and late CKD, respectively. Mean (SE) number of annual hospitalizations were 0.15 (0.01), 0.19 (0.01), and 0.42 (0.03) for participants with no CKD, early CKD, and late CKD, respectively. Participants with late CKD were more likely to have more physician visits (OR 1.81, 95% CI 1.46, 2.23) and have more hospital admissions (OR 2.12, 95% CI 1.66, 2.71) compared with participants with early CKD or no CKD. Conclusions: In this analysis, late stage CKD was associated with increased HRU, suggesting the need for early identification and treatment of CKD and its associated conditions.


Article / Publication Details

First-Page Preview
Abstract of Original Report: Laboratory Investigation

Received: 8/6/2008
Accepted: 9/4/2008
Published online: 11/27/2008

Number of Print Pages: 10
Number of Figures: 1
Number of Tables: 4

ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)

For additional information: http://www.karger.com/AJN


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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