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Table of Contents
Vol. 13, No. 5, 1974
Issue release date: 1974
Nephron 1974;13:396–403

Further Observations of Renal Insufficiency in Snakebite

Sitprija V. · Benyajati C. · Boonpucknavig V.
Department of Medicine, Chulalongkorn Hospital and Department of Pathology, Ramathibodi Hospital, Bangkok

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Acute renal insufficiency was observed in two patients bitten by Russell’s vipers. Both patients had bleeding symptoms presumably due to disseminated intravascular coagulation. There was mild intravascular hemolysis. The serum β-1 C globulin was decreased in both cases. Renal biopsy showed tubular necrosis and arteritis. By immunofluorescent study deposition of β-1 C globulin was noted in the arterial lesion, the glomerular mesangium, and the arteriolar wall. Immunoglobulin and fibrin deposits could not be detected.

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