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Vol. 200, No. 2, 2000
Issue release date: 2000

Comparative Anti-Dandruff Efficacy between a Tar and a Non-Tar Shampoo

Piérard-Franchimont C. · Piérard G.E. · Vroome V. · Lin G.C. · Appa Y.
Dermatology 2000;200:181–184 (DOI:10.1159/000018362)
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A randomized double-blind clinical study was conducted on two groups of 30 volunteers using either a non-tar shampoo (2% salicylic acid, 0.75% piroctone olamine and 0.5% elubiol) or a 0.5% coal tar shampoo. Subjects were diagnosed as having moderate to marked dandruff. The study consisted of a 3-week washout, followed by a 4-week treatment and a 4-week posttreatment regression phase. The clinical evaluations and subject self-assessments showed that the non-tar shampoo was as effective as the tar shampoo. Both received high approval ratings (≥70%). Biometrological methods proved to be more sensitive than clinical evaluations to assess the efficacy of the shampoos. The non-tar shampoo yielded a significantly better reduction of Malassezia spp. counts (p < 0.02) during the treatment phase and reduced the spontaneous increase in squamometry values (p < 0.01) during the posttreatment phase. It is concluded that a formulation associating salicylic acid, piroctone olamine and elubiol exhibited increased beneficial effects compared to the coal tar shampoo.

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