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Sacrococcygeal Teratomas: Prenatal Surveillance, Growth and Pregnancy Outcome

Wilson R.D. · Hedrick H. · Flake A.W. · Johnson M.P. · Bebbington M.W. · Mann S. · Rychik J. · Liechty K. · Adzick N.S.
Fetal Heart Program, The Center for Fetal Diagnosis and Treatment, The Children’s Hospital of Philadelphia, and Departments of Surgery, Obstetrics/Gynecology, and Pediatrics, University of Pennsylvania, School of Medicine, Philadelphia, Pa., USA Fetal Diagn Ther 2009;25:15–20 (DOI:10.1159/000188056)


Objective: Prenatal surveillance and growth characteristics are evaluated in a cohort of fetuses with sacrococcygeal teratomas (SCT) as part of risk assessment. Methods: Retrospective review of 23 fetuses with SCT: prenatal diagnosis, surveillance, delivery, and early postnatal outcome are reported. Results: Cardiac output failure physiology requires serial evaluation. The size of the SCT determines obstetrical risks and mode of delivery. An SCT growth rate approaching >150 cm3 per week may be associated with increased perinatal mortality risks. Maternal morbidity is related mainly to polyhydramnios and preterm labor. Conclusions: Perinatal mortality is approximately 43%. Maternal-fetal surgery for fetal physiologic deterioration is not frequent, but serial surveillance is required to minimize fetal morbidity/mortality and maternal morbidity. Rapid SCT growth rates may be associated with increased risk of perinatal mortality.


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