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Vol. 17, No. 3, 2000
Issue release date: 2000
Dig Surg 2000;17:306–309

Esophageal Leiomyomatosis in a Woman with a History of Vulvar Leiomyoma and Barrett’s Esophagus

A Case Report and Review of the Literature

Compagnoni G.M. · Talamonti M.S. · Joob A. · Ergun G.A. · Rao S.
Departments of Surgery, Gastroenterology and Pathology, McGaw Medical Center of Northwestern University Medical School, Chicago, Ill., USA

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Background: The diagnosis and treatment of esophageal pathology remains a challenge despite advances in preoperative endoscopy, radiographic staging, and perioperative care. Case Report: In this article, we present an interesting case of esophageal leiomyomatosis in a woman with a history of vulvar leiomyoma and Barrett’s esophagus. This paper represents the first reported simultaneous occurrence of these three pathologic entities in the English literature. Conclusions: The clinical presentation and characteristic pathologic findings in patients with esophageal leiomyomatosis are reviewed. Diagnostic and therapeutic approaches to esophageal masses are discussed including the indications for esophageal resection.

Copyright © 2000 S. Karger AG, Basel

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  1. Postlethwait RW, Musser AW: Changes in the esophagus in 1,000 autopsy specimens. J Thorac Cardiovasc Surg 1974;68:953–956.

    External Resources

  2. Seremetis MG, Lyons WS, DeGuzman VC, Peabody JW: Leiomyomata of the esophagus. Cancer 1976;38:2166–2177.

    External Resources

  3. Hall AJ: A case of diffuse fibromyoma of the esophagus causing dysphagia and death. Q J Med 1916;9:406–428.
  4. Wood DA: Primary idiopathic muscular hypertrophy of the lower esophagus with narrowing of the lumen. Arch Pathol Lab Med 1932;14:766–773.
  5. Sloper JC: Idiopathic diffuse muscular hypertrophy of the lower esophagus. Thorax 1954;9:136–146.
  6. Marsten EL, Bradshaw HH: Idiopathic muscular hypertrophy of the esophagus. J Thorac Cardiovasc Surg 1959;38:248–252.
  7. Fernandes JP, Mascarenhas MJ, daCosta JC, Correia JP: Diffuse leiomyomatosis of the esophagus: A case report and review of the literature. Dig Dis Sci 1975;20:684–690.
  8. Demian SDE, Vargas-Cortes F: Idiopathic muscular hypertrophy of the esophagus. Chest 1978;73:28–32.

    External Resources

  9. Zeller R, McLelland R, Myers B, Thompson MW: Idiopathic muscular hypertrophy of the esophagus: A case report. Gastrointest Radiol 1979;4:121–125.

    External Resources

  10. Kabuto T, Tanaguchi K, Iwanaga T, Teresawa T, Tateishi R, Taniguchi H: Diffuse leiomyomatosis of the esophagus. Dig Dis Sci 1980;25:388–391.

    External Resources

  11. Iyer SK, Chandrasekhara KY, Sutton A: Diffuse muscular hypertrophy of the esophagus. Am J Med 1986;80:849–852.

    External Resources

  12. Ikeda M, Fujino MA, Kojima Y, Nakamura T, Suzuki H: Esophageal stenosis and thickening of the muscularis propria diagnosed by endoscopic ultrasonography. Dig Endosc 1991;3:188–193.
  13. Lonsdale RN, Roberts PF, Vaughan R, Thiru S: Familial esophageal leiomyomatosis and nephropathy. Histopathology 1992;20:127–133.
  14. Cochat P, Guibaud P, Torres RG, Roussel B, Guarner V, Larbre F: Diffuse leiomyomatosis in Alport syndrome. J Pediatr 1988;113:339–343.

    External Resources

  15. Cochat P, Guyot C, Antignac C, Pracros JP, Bouvier R, Chappuis JP, Gilbert-Barness E: Alport syndrome and diffuse leiomyomatosis. Am J Dis Child 1993; 147:791–792.
  16. Wahlen T, Astedt B: Familial occurrence of coexisting leiomyoma of vulva and esophagus. Acta Obstet Gynecol Scand 1965;44:197–203.
  17. Schapiro RL, Sancrock AR: Esophagogastric and vulvar leiomyomatosis: A new radiologic syndrome. J Can Assoc Radiol 1973;24:184–190.

    External Resources

  18. Guarner V, Torres RG: Diffuse leiomyomatosis of the esophagus, tracheobronchial, genital, and renal insufficiency; in De Meester TR, Skinner DB (eds): Esophageal Disorders: Pathophysiology and Therapy. New York, Raven Press, 1985, pp 447–457.
  19. Faber K, Jones M, Spratt D, Tarraza H: Vulvar leiomyomatosis in a patient with esophagogastric leiomyomatosis: Review of the syndrome. Gynecol Oncol 1991;41:92–94.

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