Journal Mobile Options
Table of Contents
Vol. 64, No. 3, 1997
Issue release date: 1997
Respiration 1997;64:194–199
(DOI:10.1159/000196670)

Predictive Diagnostic Value of Clinical Assessment and Nonlaboratory Monitoring System Recordings in Patients with Symptoms Suggestive of Obstructive Sleep Apnea Syndrome

Schäfer H. · Ewig S. · Hasper E. · Lüderitz B.
Department of Internal Medicine, University of Bonn, Germany

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

Obstructive sleep apnea syndrome (OSA) is of increasing importance because of its high prevalence and danger of morbidity to untreated patients. Diagnostic procedures need simplification. We evaluated the qualitative value of a stepwise diagnostic approach using clinical assessment and a home-based screening device according to current recommendations. Methods: We investigated 114 patients with symptoms suggestive of obstructive sleep apnea syndrome by means of their clinical features, questionnaire responses, four-channel nonlaboratory monitoring (NLM) and full polysomnography. Operative indices in the diagnosis of OSA were calculated. Results: A significant correlation (r = 0.7; p < 0.0001) was found between the oxygen desaturation index (ODI) and the respiratory disturbance index (RDI). The calculation of the difference between ODI by NLM and RDI by polysomnography showed a lack of agreement. Home-based monitoring revealed a high sensitivity (94%) but a low specificity (41 %) in diagnosing OSA. However, a combination of clinical features, questionnaires and pulse oximetry achieved a specificity of 92%. Conclusion: Home-based monitoring provides reasonable negative predictive values in the diagnosis of OSA syndrome in symptomatic patients. It therefore qualifies as a screening method. Combined with clinical features and questionnaires it provides high positive predictive values and may therefore prove useful in simplifying diagnostic procedures.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.


Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50