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Table of Contents
Vol. 37, No. 2, 2000
Issue release date: February 2000
Section title: Andrology – Erectile Dysfunction
Eur Urol 2000;37:172–175
(DOI:10.1159/000020135)

Increased Nitric Oxide Production in the Spermatic Vein of Patients with Varicocele

Ozbek E. · Turkoz Y. · Gokdeniz R. · Davarci M. · Ozugurlu F.
Departments of aUrology, bOstetrics and Gynecology, and cBiochemistry, Inonu University School of Medicine, Malatya, Turkey

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Article / Publication Details

First-Page Preview
Abstract of Andrology – Erectile Dysfunction

Published online: 2/17/2000

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 1

ISSN: 0302-2838 (Print)
eISSN: 1421-993X (Online)

For additional information: http://www.karger.com/EUR

Abstract

Objective: To define the level of nitric oxide (NO) in the spermatic vein of patients with varicocele and its relation with male infertility.

Materials and Methods: Following physical and color Doppler ultrasonographic examination, whole blood samples were drawn from a peripheral vein and a dilated varicocele vein from fourteen patients with clinically palpable varicocele (G2–3) before ligation. NO levels in the serum were determined as total nitrite by Greiss reaction and results were compared with Mann–Whitney U test.

Results: NO levels in the internal spermatic vein were 36.05 ± 8.92 μmol/l, compared to 19.41 ± 4.12 μmol/l in the peripheral vein and the difference was statistically significant (p < 0.01).

Conclusion: In view of our results, increased NO levels in the dilated varicocele vein might be responsible for spermatozoa dysfunction.


Article / Publication Details

First-Page Preview
Abstract of Andrology – Erectile Dysfunction

Published online: 2/17/2000

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 1

ISSN: 0302-2838 (Print)
eISSN: 1421-993X (Online)

For additional information: http://www.karger.com/EUR


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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