Objective: To present 2 cases of primary breast abscesses caused by Mycobacterium tuberculosis mimicking pyogenic abscesses in healthy young females. Clinical Presentation and Intervention: Two young non-lactating Indonesian and Indian women, aged 27 and 29 years old, respectively, presented with breast abscesses caused by M.tuberculosis. The breasts presented as huge, swollen, hot, tender masses with a discharge at the subareolar site. Surgical drainage revealed deep abscess with copious amount of pus, samples of which were positive for acid-fast bacilli (AFB) and later confirmed as M.tuberculosis by positive cultures in Becton Dickinson BBL Migit and BACTEC 12B media. The initial therapies with clindamycin were changed to 4 anti-tuberculous drugs as soon as the smears showed the presence of AFB. The patients were discharged a week later, but both were lost to follow-up. Conclusion: Mammary tuberculosis should be considered in the differential diagnosis of breast lesion, especially in patients from endemic areas.
© 2009 S. Karger AG, Basel
- Mycobacterium tuberculosis
- Pyogenic abscess
- Breast abscess
- Tewari M, Shukla HS: Breast tuberculosis: diagnosis, clinical features and management. Indian J Med Res 2005;122:103–110.
- Hale JA, Peters GN, Cheek JH: Tuberculosis of the breast: rare but still extant. Review of the literature and report of an additional case. Am J Surg 1985;150:620–624.
- Khanna R, Prasanna GV, Gupta P, Kumar M, Khanna S, Khanna AK: Mammary tuberculosis: report on 52 cases. Postgrad Med J 2002;78:422–424.
- Ozol D, Bozer M, Bayrak R: Breast tuberculosis. Saudi Med J 2006;27:1066–1068.
- Akcay MN, Saglam L, Polat P, Erdogan F, Albayrak Y, Povoski SP: Mammary tuberculosis – importance of recognition and differentiation from that of a breast malignancy: report of three cases and review of the literature. World J Surg Oncol 2007;5:67.
- Al-Marri MR, Almosleh A, Almoslmani Y: Primary tuberculosis of the breast in Qatar: ten year experience and review of the literature. Eur J Surg 2000;166:687–690.
- Harris SH, Khan MA, Khan R, Haque F, Syed A, Ansari MM: Mammary tuberculosis: analysis of thirty-eight patients. ANZ J Surg 2006;76:234–237.
- Gupta V, Mohan H, Jain P, Surinder S, Singla N: Tuberculous mastitis: a report of two cases in elderly females. Jpn J Infec Dis 2006;59:279–280.
- Indumathi CK, Alladi A, Dinakar C, Rout PL: Tuberculosis of the breast in an adolescent girl: a rare presentation. J Trop Pediatr 2006;53:133–134.
- Bani-Hani KE, Yaghan RJ, Matalka II, Mazahreh TS: Tuberculous mastitis: a disease not to be forgotten. Int J Tuberc Lung Dis 2005;9:920–925.
- Verfaillie G, Goossens A, Lamote J: Atypical mycobacterium breast infection. Breast J 2004;10:60.
- Winzer KJ, Menenakos J, Braumann C, Mueller JM: Breast mass due to pectoral muscle tuberculosis mimicking breast cancer in male patients. Int J Infect Dis 2005;9:176–177.
- Da Silva BB, Dos Santos LG, Costa PVL, Pires CG, Borges AS: Clinical case report: primary tuberculosis of the breast mimicking carcinoma. Am J Trop Med Hyg 2005;73:975–976.
Prof. Vincent O. Rotimi, MD, PhD
Department of Microbiology
Faculty of Medicine, Kuwait University
PO Box 24923, Safat 13110 (Kuwait)
Tel. +965 498 6509, E-Mail firstname.lastname@example.org
Received: November 21, 2007
Revised: April 27, 2008
Published online: April 06, 2009
Number of Print Pages : 3
Number of Figures : 0, Number of Tables : 1, Number of References : 13
Medical Principles and Practice (International Journal of the Kuwait University Health Sciences Centre)
Vol. 18, No. 3, Year 2009 (Cover Date: April 2009)
Journal Editor: Owunwanne A. (Kuwait)
ISSN: 1011-7571 (Print), eISSN: 1423-0151 (Online)
For additional information: http://www.karger.com/MPP
Open Access License / Drug Dosage / Disclaimer
Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license
), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.