Journal Mobile Options
Table of Contents
Vol. 36, No. 1, 1990
Issue release date: 1990
Gerontology 1990;36:28–35

Skin Thickness Changes in Normal Aging Skin

Branchet M.C. · Boisnic S. · Frances C. · Robert A.M.
aLaboratoire de Biochimie du Tissu Conjonctif, UA CNRS 1174, Faculté de Médecine, Université Paris XII, Créteil; bService d’Anatomie et de Cytologie Pathologique, Groupe Hospitalier Pitié-Salpêtrière, cService de Médecine Interne, Groupe Hospitalier Pitié-Salpêtrière, Paris, France

Individual Users: Register with Karger Login Information

Please create your User ID & Password

Contact Information

I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in


The age-dependent decrease of skin thickness was studied with a morphometric procedure on upper inner arm skin biopsies. Epidermal thickness decreased somewhat faster in men (7.2 % of the original value/decade) than in women (5.7 %). The total dermal thickness decreased at about the same rate in men and women (6%/decade). The thickness of the superficial layer of the dermis exhibited a biphasic evolution with age and these variations were not significantly different between men and women because of the large individual variations. This may be due partially to the difficulties of delineating with precision the limit between superficial and reticular dermis. These results are somewhat lower than those obtained by physical measurements of skin thickness. This may be due to fixation artifacts and also to the overestimation of skin thickness by physical measurements.

Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50