The Validity, Reliability and Clinical Utility of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in Patients with Cerebral Small Vessel DiseaseWong A. · Xiong Y.Y. · Kwan P.W.L. · Chan A.Y.Y. · Lam W.W.M. · Wang K. · Chu W.C.W. · Nyenhuis D.L. · Nasreddine Z. · Wong L.K.S. · Mok V.C.T.
aDepartment of Medicine and Therapeutics, and bDepartment of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong, SAR, China; cDepartment of Neurology and Rehabilitation Medicine, University of Illinois at Chicago, Center for Stroke Research, Chicago, Ill., USA; dCenter for Clinical Research, Neurology Service, Hôpital Charles LeMoyne, Quebec, Que., Canada
Background/Aims: To evaluate the psychometric properties of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in patients with cerebral small vessel disease (SVD). Methods: 40 SVD patients and 40 matched controls were recruited. Concurrent and criterion validity, inter-rater and test-retest reliability, internal consistency of the HK-MoCA were examined and clinical observations were made. Results: Performance on the HK-MoCA was significantly predicted by both executive (β = 0.23, p = 0.013) and non-executive (β = 0.64, p < 0.001) composite scores. It differentiated SVD patients from controls (area under the curve = 0.81, p < 0.001) with an optimal cutoff at 21/22. Reliability, internal consistency and clinical utility were good. Conclusion: The HK-MoCA is a useful cognitive screening instrument for use in SVD patients.
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