Special Topic Section: Epigenomics in Psychiatry Editor: T. Kinoshita Review
- Epigenetic profiling
- Major mental disorders
Epigenetic alterations such as DNA methylation and histone modifications are important in the etiology or pathophysiology of mental disorders. Here, we review recent studies on the relationship between DNA methylation and major mental disorders. We will focus on the role of DNA methylation in postmitotic neurons, intra- and interindividual variations in DNA methylation, the possible involvement of methionine metabolism pathways, and candidate and genome-wide DNA methylation as they relate to mental disorders.
Copyright © 2009 S. Karger AG, Basel
Laboratory for Molecular Dynamics of Mental Disorders
RIKEN Brain Science Institute
2-1 Hirosawa, Wako, Saitama 351-0198 (Japan)
Tel. +81 48 467 6949, Fax +81 48 467 6947, E-Mail firstname.lastname@example.org
Received: October 1, 2008
Accepted after revision: December 22, 2008
Published online: August 14, 2009
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 0, Number of References : 97
Neuropsychobiology (International Journal of Experimental and Clinical Research in Biological Psychiatry, Pharmacopsychiatry, Biological Psychology/Pharmacopsychology and Pharmacoelectroencephalography)
Vol. 60, No. 1, Year 2009 (Cover Date: September 2009)
Journal Editor: Strik W. (Bern)
ISSN: 0302-282X (Print), eISSN: 1423-0224 (Online)
For additional information: http://www.karger.com/NPS
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