Delirium is an important neuropsychiatric syndrome in the elderly that is associated with an increase in mortality, impaired physical and cognitive recovery, and increased healthcare costs. Two important gaps in daily practice with delirium are the pathophysiological obscurity and the low recognition rates. Genetics offers the possibility to contribute knowledge to both of these gaps with its unique and diverse techniques. However, genetic studies in delirium have been scarce until recently, due to the nature of the diagnosis, the etiology of the syndrome, and the pitfalls inherent in the design of genetic studies. This review describes the barriers of this field of research and the implications for our current knowledge of delirium.
© 2009 S. Karger AG, Basel
- Delirium, diagnosis
- Risk factors, delirium
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B.C. van Munster
Department of Clinical Epidemiology, Biostatistics and Bioinformatics
Room J1B-207-1, Academic Medical Centre, University of Amsterdam, PO Box 22660
NL–1100 DD Amsterdam (The Netherlands)
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Accepted: May 29, 2009
Published online: August 28, 2009
Number of Print Pages : 9
Number of Figures : 1, Number of Tables : 2, Number of References : 52
Dementia and Geriatric Cognitive Disorders
Vol. 28, No. 3, Year 2009 (Cover Date: October 2009)
Journal Editor: Chan-Palay V. (New York, N.Y.)
ISSN: 1420-8008 (Print), eISSN: 1421-9824 (Online)
For additional information: http://www.karger.com/DEM
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