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Table of Contents
Vol. 52, No. 6, 2009
Issue release date: November 2009
Section title: Original Paper
Intervirology 2009;52:310–320

Epidemiology of Human Influenza A and B Viruses in Myanmar from 2005 to 2007

Dapat C.a · Saito R.a · Kyaw Y.c · Naito M.b · Hasegawa G.b · Suzuki Y.a · Dapat I.C.a · Zaraket H.a · Cho T.M.d · Li D.a · Oguma T.a · Baranovich T.a · Suzuki H.a
aDepartment of Public Health and bDivision of Cellular and Molecular Pathology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan; cChest Medical Unit, Sanpya Hospital, and dRespiratory Medicine Department, Yangon General Hospital, Yangon, Myanmar
email Corresponding Author

Clyde Dapat

Department of Public Health

Graduate School of Medical and Dental Sciences, Niigata University

1-757 Asahimachi-dori, Niigata 951-8510 (Japan)

Tel. +81 25 227 2129, Fax +81 25 227 0765, E-Mail clyde@med.niigata-u.ac.jp


  1. Escuret V, Frobert E, Bouscambert-Duchamp M, et al: Detection of human influenza A (H1N1) and B strains with reduced sensitivity to neuraminidase inhibitors. J Clin Virol 2008;41:25–28.
  2. Suzuki H, Saito R, Masuda H, et al: Emergence of amantadine-resistant influenza A viruses: epidemiological study. J Infect Chemother 2003;9:195–200.
  3. Gachara G, Ngeranwa J, Magana JM, et al: Influenza virus strains in Nairobi, Kenya. J Clin Virol 2006;35:117–118.
  4. Hasegawa G, Kyaw Y, New HM, et al: Epidemiological study of influenza virus infections in Yangon, Myanmar. Trop Med Health 2006;34:3–6.
    External Resources
  5. Viboud C, Alonso WJ, Simonsen L: Influenza in tropical regions. PLoS Med 2006;3:468–471.
    External Resources
  6. Russell CA, Jones TC, Barr IG, et al: The global circulation of seasonal influenza A (H3N2) viruses. Science 2008;320:340–346.
  7. Li D, Saito R, Le MTQ, et al: Genetic analysis of influenza A/H3N2 and A/H1N1 viruses circulating in Vietnam from 2001 to 2006. J Clin Microbiol 2008;46:399–405.
  8. Bright RA, Medina MJ, Xu X, et al: Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 2005;366:1175–1181.
  9. Barr IG, Hurt AC, Iannello P, et al: Increased amantadine resistance in influenza A (H3) viruses in Australia and neighboring countries in 2005. Antiviral Res 2007;73:112–117.
  10. Saito R, Li D, Suzuki H: Amantadine-resistant influenza A (H3N2) virus in Japan, 2005–2006. N Engl J Med 2007;356:312–313.
  11. Bright RA, Shay DK, Shu B, et al: Adamantane resistance among influenza A viruses isolated early during the 2005–2006 influenza season in the United States. JAMA 2006;295:891–894.
  12. Hasegawa G, Kyaw Y, Li D, et al: Influenza virus infections in Yangon, Myanmar. J Clin Virol 2006;37:233–234.
  13. Center for Disease Control: Concepts and Procedures for Laboratory-Based Influenza Surveillance. Atlanta, US Department of Health, Public Health Service, 1982.
  14. Hoffmann E, Stech J, Guan Y, et al: Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol 2001;146:2275–2289.
  15. Burland TG: DNASTAR’s Lasergene sequence analysis software. Methods Mol Biol 2000;132:71–91.
  16. Tamura K, Dudley J, Nei M, et al: MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 2007;24:1596–1599.
  17. Hay AJ, Wolstenholme AJ, Skehel JJ, et al: The molecular basis of the specific anti-influenza action of amantadine. EMBO J 1985;4:3021–3024.
  18. Schnell JR, Chou JJ: Structure and mechanism of the M2 proton channel of influenza A virus. Nature 2008;451:591–595.
  19. WHO: Recommended composition of influenza virus vaccines for use in the 2005–2006 influenza season. Wkly Epidemiol Rec 2005;80:65–76.
    External Resources
  20. WHO: Recommended composition of influenza virus vaccines for use in the 2007–2008 influenza season. Wkly Epidemiol Rec 2007;82:69–74.
    External Resources
  21. Rambaut A, Pybus OG, Nelson MI, et al: The genomic and epidemiological dynamics of human influenza A virus. Nature 2008;453:615–619.
  22. Shek LP, Lee BW: Epidemiology and seasonality of respiratory tract virus infections in the tropics. Paediatr Respir Rev 2003;4:105–111.
  23. Simmerman JM, Thawatsuoha P, Kingnate D, et al: Influenza in Thailand: a case study for middle income countries. Vaccine 2004;23:182–187.
  24. Nguyen HLK, Saito R, Ngiem HK, et al: Epidemiology of influenza in Hanoi, Vietnam, 2001–2003. J Infect 2007;55:58–63.
  25. Tsai HP, Kuo PH, Liu CC, et al: Respiratory viral infections among pediatric inpatients and outpatients in Taiwan from 1997 to 1999. J Clin Microbiol 2001;39:111–118.
  26. WHO: Summary of influenza activity, September 2004–August 2005. Wkly Epidemiol Rec 2005;80:353–360.
    External Resources
  27. WHO: Influenza in the world, September 2006–August 2007. Wkly Epidemiol Rec 2007;82:357–360.
    External Resources
  28. Saito R, Suzuki Y, Li D, et al: Increased incidence of adamantine-resistant influenza A(H1N1) and A(H3N2) viruses during the 2006–2007 influenza season in Japan. J Infect Dis 2008;197:630–632.
  29. Zaraket H, Dbaibo G, Salam O, et al: Influenza virus infections in Lebanese children in the 2007–2008 season. Jpn J Infect Dis 2009;62:137–138.
  30. Reyes F, Aziz S, Winchester B, et al: Influenza in Canada: 2007–2008 season update. Can Commun Dis Rep 2008;34:1–9.
    External Resources
  31. CDC: Influenza activity – United States and worldwide, 2007–2008 season. MMWR 2008;57:692–697.
    External Resources
  32. Barr IG, Deng YM, Iannello P, et al: Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries. Antiviral Res 2008;80:200–205.
  33. WHO: Recommended composition of influenza virus vaccines for use in the 2008–2009 influenza season. Wkly Epidemiol Rec 2008;83:77–88.
    External Resources
  34. Saito R, Li D, Suzuki Y, et al: High prevalence of amantadine-resistance influenza A (H3N2) in six prefectures, Japan, in the 2005–2006 season. J Med Virol 2007;79:1569–1576.
  35. Hay AJ, Gregory V, Douglas AR, et al: The evolution of human influenza viruses. Phil Trans R Soc Lond B 2001;356:1861–1870.
  36. Berton MT, Naeve CW, Webster RG: Antigenic structure of the influenza B virus hemagglutinin: nucleotide sequence analysis of antigenic variants selected with monoclonal antibodies. J Virol 1984;52:919–927.
  37. Lin YP, Gregory V, Bennett H, et al: Genetic reassortment among recently circulating human influenza A and B viruses. Int Congr Ser 2004;1263:178–183.
  38. Shaw MW, Xu X, Li Y, et al: Reappearance and global spread of variants of influenza B/Victoria/2/87 lineage viruses in the 2000–2001 and 2001–2002 seasons. Virology 2002;303:1–8.
  39. Jian JW, Lai CT, Kuo CY, et al: Genetic analysis and evaluation of the reassortment of influenza B viruses isolated in Taiwan during the 2004–2006 and 2006–2007 epidemics. Virus Res 2008;131:243–249.
  40. Lin JH, Chiu SC, Shaw MW, et al: Characterization of the epidemic influenza B viruses isolated during 2004–2005 season in Taiwan. Virus Res 2007;124:204–211.
  41. Chen R, Holmes EC: The evolutionary dynamics of human influenza B virus. J Mol Evol 2008;66:655–663.
  42. Besselar TG, Botha L, McAnerney JM, et al: Antigenic and molecular analysis of influenza A (H3N2) virus strains isolated from a localized influenza outbreak in South Africa in 2003. J Med Virol 2004;73:71–78.
  43. Nakagawa N, Kubota R, Maeda A, et al: Heterogeneity of influenza B virus strains in one epidemic season differentiated by monoclonal antibodies and nucleotide sequences. J Clin Microbiol 2000;38:3467–3469.