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Table of Contents
Vol. 56, No. 2, 2010
Issue release date: March 2010
Section title: Short Communication
Gerontology 2010;56:150–156
(DOI:10.1159/000237874)

Noninvasive Home Mechanical Ventilation in Elderly Patients

Crespo A. · Muñoz X. · Torres F. · Martí S. · Ferrer J. · Morell F.
aServei de Pneumologia, Hospital Universitari Vall d’Hebron, bDepartament de Biologia Celular, Fisiologia, Inmunologia, Facultat de Medicina, cDepartament de Medicina, i dLaboratori de Bioestadística i Epidemiologia, Universitat Autónoma de Barcelona, Barcelona, España

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Article / Publication Details

First-Page Preview
Abstract of Short Communication

Received: 3/20/2009
Accepted: 5/28/2009
Published online: 9/10/2009

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 5

ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)

For additional information: http://www.karger.com/GER

Abstract

Study Objective: To determine the short- and long-term benefits of noninvasive home mechanical ventilation (NIHMV) in patients aged 65 and older who were eligible for this treatment. Design and Setting: This retrospective, comparative, longitudinal study was carried out in a tertiary care hospital in Barcelona (Spain). Patients and Methods: The study included all patients in whom NIHMV with a nasal mask was established in the period from 1998 to 2001. Patients were divided into 3 groups according to age: group 1 (n = 10) ≧75; group 2 (n = 40) 65–74, and group 3 (n = 41) <65 years old. Clinical characteristics, pulmonary function results, and arterial blood gas findings were assessed in all patients before starting ventilation and after 6 months. Measurements and Results: Statistically significant improvements in PaO2 (13.4, 10, and 15.3 mm Hg for groups 1–3) and PaCO2 (–17.6, –9.6 and –12.8 mm Hg for groups 1–3) were found at 6 months (p < 0.001 in all cases). There were no significant differences between the groups in blood gas parameters and treatment compliance. The incidence of related adverse events was not statistically different between the study groups (40%, 35% and 32% for groups 1–3; p = 0.859). Conclusions: NIHMV is effective in all patients for whom it is indicated, regardless of their age.


Article / Publication Details

First-Page Preview
Abstract of Short Communication

Received: 3/20/2009
Accepted: 5/28/2009
Published online: 9/10/2009

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 5

ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)

For additional information: http://www.karger.com/GER


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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