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Vol. 27, No. 3, 1981
Issue release date: 1981
Chemotherapy 1981;27:220–223

Study of the Efficacy of Compound Go.9333 (Ciba-Geigy) in Hookworm Infestation

Singh D.S. · Bala-Subramaniam R. · Bhatia V.N. · Kumar V. · Chandrasekar S.
Department of Medicine (Division of Gastroenterology) and Microbiology (Parasitology Section), Jipmer, Pondicherry, India

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50 cases with hookworm infestation were studied to find out the species of the parasite, 25 of them were included for a double-blind trial of compound Go.9333 (Ciba-Geigy)/placebo. Results of the study revealed predominance of Necator americanus (96%) in and around Pondicherry, South India. Compound Go.9333 was found to be very effective in the treatment of hookworm infestation. Side effects were minor and were not of much significance. The drug was well accepted and tolerated by most of the cases. On the basis of the present study, compound Go.9333 can be recommended for the treatment of hookworm infestation.

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