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Table of Contents
Vol. 19, No. 1, 2010
Issue release date: December 2009
Section title: Mini Review
Open Access Gateway
Med Princ Pract 2010;19:82–85

Prostatic Ductal Adenocarcinoma: A Mini Review

Epstein J.I.
Departments of Pathology, Urology, and Oncology, The Johns Hopkins Hospital, Baltimore, Md., USA
email Corresponding Author

Prof. Jonathan I. Epstein

Departments of Pathology, Urology, and Oncology, The Johns Hopkins Hospital

600 N. Wolfe Street

Baltimore, MD 21287 (USA)

Tel. +1 410 955 5043, Fax +1 410 955 0115, E-Mail


  1. Brinker DA, Potter SR, Epstein JI: Ductal adenocarcinoma of the prostate diagnosed on needle biopsy: correlation with clinical and radical prostatectomy findings and progression. Am J Surg Pathol 1999;23:1471–1479.
  2. Bostwick DG, Kindrachuk RW, Rouse RV: Prostatic adenocarcinoma with endometrioid features: clinical, pathologic, and ultrastructural findings. Am J Surg Pathol 1985;9:595–609.
  3. Christensen WN, Steinberg G, Walsh PC, Epstein JI: Prostatic duct adenocarcinoma: findings at radical prostatectomy. Cancer 1991;67:2118–2124.
  4. Epstein JI, Woodruff JM: Adenocarcinoma of the prostate with endometrioid features: a light microscopic and immunohistochemical study of ten cases. Cancer 1986;57:111–119.
  5. Greene LF, Farrow GM, Ravits JM, Tomera FM: Prostatic adenocarcinoma of ductal origin. J Urol 1979;121:303–305.
  6. Melicow MM, Tannenbaum M: Endometrial carcinoma of uterus masculinus (prostatic utricle): report of 6 cases. J Urol 1971;106:892–902.
  7. Hameed O, Humphrey PA: Stratified epithelium in prostatic adenocarcinoma: a mimic of high-grade prostatic intraepithelial neoplasia. Mod Pathol 2006;19:899–906.
  8. Tavora F, Epstein JI: High-grade prostatic intraepithelial neoplasia-like ductal adenocarcinoma of the prostate: a clinicopathologic study of 28 cases. Am J Surg Pathol 2008;32:1060–1067.
  9. Herawi M, Epstein JI: Immunohistochemical antibody cocktail staining (p63/HMWCK/AMACR) of ductal adenocarcinoma and Gleason pattern 4 cribriform and noncribriform acinar adenocarcinomas of the prostate. Am J Surg Pathol 2007;31:889–894.
  10. Samaratunga H, Singh M: Distribution pattern of basal cells detected by cytokeratin 34 beta E12 in primary prostatic duct adenocarcinoma. Am J Surg Pathol 1997;21:435–440.
  11. Owens CL, Epstein JI, Netto GJ: Distinguishing prostatic from colorectal adenocarcinoma on biopsy samples: the role of morphology and immunohistochemistry. Arch Pathol Lab Med 2007;131:599–603.
  12. Grignon DJ: Unusual subtypes of prostate cancer. Mod Pathol 2004;17:316–327.
  13. Hameed O, Humphrey PA: Immunohistochemistry in diagnostic surgical pathology of the prostate. Semin Diagn Pathol 2005;22:88–104.
  14. Mai KT, Collins JP, Veinot JP: Prostatic adenocarcinoma with urothelial (transitional cell) carcinoma features. Appl Immunohistochem Mol Morphol 2002;10:231–236.
  15. Oxley J, Abbott C. Thrombomodulin immunostaining and ductal carcinoma of the prostate. Histopathology 1998;33:391–392.
  16. Tu SM, Reyes A, Maa A, Bhowmick D, Pisters LL, Pettaway CA, Lin SH, Troncoso P, Logothetis CJ: Prostate carcinoma with testicular or penile metastases. Clinical, pathologic, and immunohistochemical features. Cancer 2002;94:2610–2617.
  17. Copeland JN, Amin MB, Humphrey PA, Tamboli P, Ro JY, Gal AA: The morphologic spectrum of metastatic prostatic adenocarcinoma to the lung: special emphasis on histologic features overlapping with other pulmonary neoplasms. Am J Clin Pathol 2002;117:552–557.
  18. Ro JY, Ayala AG, Wishnow KI, Ordóñez NG: Prostatic duct adenocarcinoma with endometrioid features: immunohistochemical and electron microscopic study. Semin Diagn Pathol 1988;5:301–311.
  19. Epstein JI, Allsbrook WC Jr, Amin MB, Egevad LL, ISUP Grading Committee: The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. Am J Surg Pathol 2005;29:1228–1242.