Journal Mobile Options
Table of Contents
Vol. 7, No. 3, 1998
Issue release date: July–September 1998
Section title: Case Report
Open Access Gateway
Med Principles Pract 1998;7:215–222
(DOI:10.1159/000026045)

Rising Incidence of Beta-Lactam Resistance among Pneumococci in Kuwait: Failure of Cefotaxime Therapy in Pneumococcal Meningitis

Johny M.a · Narayanan S.b · Murad M.A.a
Departments of a Laboratory Medicine and b Medicine, Al-Amiri Hospital, Ministry of Public Health, Kuwait
email Corresponding Author

Dr. Molly Johny

Microbiology Unit, Department of Laboratory Medicine

Al-Amiri Hospital, PO Box 4077

13041 Safat (Kuwait)

Fax +965 2465299


References

  1. Appelbaum PC: Antimicrobial resistance in Streptococcus pneumoniae: An overview. Clin Infect Dis 1992;15:77–83.
  2. National Committee for Clinical Laboratory Standards: Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically: Approved standard. NCCLS Document M7-A3, ed 3. Villanova, NCCLS, 1993.
  3. Weingarten RD, Markiewicz Z, Gilbert DN: Meningitis due to penicillin resistant Streptococcus pneumoniae in adults. Rev Infect Dis 1990;12:118–124.
  4. Bradley JS, Connor JD: Ceftriaxone failure in meningitis caused by Streptococcus pneumoniae with reduced susceptibility to β-lactam antibiotics. Pediatr Infect Dis J 1991;10:871–873.
  5. Sloas MM, Barret FF, Chesney PJ, English B, Hill BC, Tenover FC, Leggiadro RJ: Cephalosporin treatment failure in penicillin and cephalosporin resistant Streptococcus pneumoniae meningitis. Pediatr Infect Dis J 1992;11:662–666.
    External Resources
  6. Catalan MJ, Fernandez JM, Vazquez A, de Seijas EV, Suarez A, de Quiros ATL: Failure of cefotaxime in the treatment of meningitis due to relatively resistant Streptococcus pneumoniae. Clin Infect Dis 1994;18:766–769.
    External Resources
  7. Jacoby GA: Prevalence and resistance mechanisms of common bacterial respiratory pathogens. Clin Infect Dis 1994;18:951–957.
    External Resources
  8. Zighelboim S, Tomasz A: Multiple antibiotic resistance in South African strains of Streptococcus pneumoniae: Mechanism of resistance to β-lactam antibiotics. Rev Infect Dis 1981;3:267–276.
  9. Johny M, Shaltout AA, Menon NK, Jamil AS: Pneumococci relatively resistant to penicillin: Report of four cases of meningitis from Kuwait. Med Principles Pract 1992/93;3:54–56.
  10. Johny M, Anton AY, Murad MA: Relative resistance of pneumococci to penicillin: Detection and prevalence in Kuwait. Med Principles Pract 1992/93;3:167–170.
  11. Doern GV: Susceptibility tests of fastidious bacteria; in Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (eds): Manual of Clinical Microbiology, ed 6. Washington, American Society for Microbiology, 1995, pp 1342–1347.
  12. Woods GL, Washington JA: Antibacterial susceptibility tests: Dilution and disc diffusion methods; in Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (eds): Manual of Clinical Microbiology, ed 6. Washington, American Society for Microbiology, 1995, pp 1327–1341.
  13. Doern GV, Brueggemann A, Holley HP Jr, Rauch AM: Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: Results of a 30-center national surveillance study. Antimicrob Agents Chemother 1996;40:1208–1213.
  14. Shibl AM, Hussein SS: Surveillance of Streptococcus pneumoniae serotypes in Riyadh and their susceptibility to penicillin and other commonly prescribed antibiotics. J Antimicrob Chemother 1992;29:149–157.
    External Resources
  15. Jacobs MR: Treatment and diagnosis of infections caused by drug- resistant Streptococcus pneumoniae. Clin Infect Dis 1992;15:119–127.
  16. Jorgenson JH, Ferraro MJ, McElmeel ML, Spargo J, Swenson JM, Tenover FC: Detection of penicillin and extended spectrum cephalosporin resistance among Streptococcus pneumoniae clinical isolates by use of the E test. J Clin Microbiol 1994;32:159–163.
  17. Johny M, Babelly M, Al-Obaid EA, Murad MA: Antimicrobial resistance of pneumococci isolated in Kuwait: Efficacy of E test for determination of MIC. J Kwt Med Assoc 1997;in press.
  18. Koornhof HJ, Wasas A, Klugman K: Antimicrobial resistance in Streptococcus pneumoniae: A South African perspective. Clin Infect Dis 1992;15:84–94.
  19. Viladrich PF, Gudiol F, Linares J, Pallares R, Sabate I, Rufi G, Ariza J: Evaluation of vancomycin for therapy of adult pneumococcal meningitis. Antimicrob Agents Chemother 1991;35:2467–2472.
    External Resources
  20. Lonks JE, Medeiros AA: The growing threat of antibiotic resistant Streptococcus pneumoniae. Med Clin North Am 1995;79:523–535.